Associate Scientist

Secant Group

Telford (PA)

On-site

USD 60,000 - 90,000

Full time

4 days ago
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Job summary

Secant Group seeks an Associate Scientist to support formulation development and characterization of biomaterial-based implants and drug-delivery devices. You will work in a fast-paced, multidisciplinary team to advance polymeric systems for controlled release and implantable applications.

You will perform pre-formulation studies, characterize drug-polymer interactions using DSC/TGA, and conduct dissolution and degradation testing with HPLC, FTIR, and Raman techniques, contributing to project

Qualifications

  • Formulate and characterize polymeric materials for implants and drug-delivery devices.

Responsibilities

  • Formulate and characterize polymeric materials designed for drug-eluting and non-drug-eluting implantable devices to support customer projects and internal investigations.
  • Execute pre-formulation studies, such as drug particle size analysis, SEM, light microscopy, milling, and sieving.
  • Characterize polymers and drug-polymer physiochemical interactions using DSC, TGA, rheometry.
  • Analyze formulations using FTIR and Raman spectroscopy to determine drug-polymer mixing efficiency, drug loading, and content uniformity.
  • Set up and run dissolution studies and analyze dissolution media to determine drug release profiles using HPLC to quantify drug concentration.
  • Set up and run degradation studies and analyze sample weight, dimensions, and topography to determine polymer degradation behavior.
  • Perform wet chemistry experiments, like residual monomer extractions, Karl Fischer titrations, and acid/base titrations.
  • Collaborate with other teammates within R&D to achieve project goals.

Skills

Polymer formulation
Drug delivery devices
Analytical methods
DSC/TGA
HPLC analysis
Rheometry
FTIR spectroscopy
Raman spectroscopy
Dissolution testing
Degradation studies

Tools

DSC instrument
TGA instrument
HPLC
Rheometer
FTIR spectrometer
Raman spectrometer
SEM
Light microscope

Job description

What We Are Looking For

The Associate Scientist position is a laboratory-based scientific role in a fast-paced, multidisciplinary team environment. In this role, you will be supporting product formulation development and characterization focused on biomedical implants and pharmaceutical devices for controlled drug delivery utilizing Secant Group’s biomaterial platform.

What You Will Do
  • Formulate and characterize polymeric materials designed for drug-eluting and non-drug-eluting implantable devices to support customer projects and internal investigations.
  • Execute pre-formulation studies, such as drug particle size analysis, SEM, light microscopy, milling, and sieving.
  • Characterize polymers and drug-polymer physiochemical interactions using DSC, TGA, rheometry.
  • Analyze formulations using FTIR and Raman spectroscopy to determine drug-polymer mixing efficiency, drug loading, and content uniformity.
  • Set up and run dissolution studies and analyze dissolution media to determine drug release profiles using HPLC to quantify drug concentration.
  • Set up and run degradation studies and analyze sample weight, dimensions, and topography to determine polymer degradation behavior.
  • Perform wet chemistry experiments, like residual monomer extractions, Karl Fischer titrations, and acid/base titrations.
  • Collaborate with other teammates within R&D to achieve project goals.
Who You Are
  • Formulate and characterize polymeric materials designed for drug-eluting and non-drug-eluting implantable devices to support customer projects and internal investigations.
  • Execute pre-formulation studies, such as drug particle size analysis, SEM, light microscopy, milling, and sieving.
  • Characterize polymers and drug-polymer physiochemical interactions using DSC, TGA, rheometry.
  • Analyze formulations using FTIR and Raman spectroscopy to determine drug-polymer mixing efficiency, drug loading, and content uniformity.
  • Set up and run dissolution studies and analyze dissolution media to determine drug release profiles using HPLC to quantify drug concentration.
  • Set up and run degradation studies and analyze sample weight, dimensions, and topography to determine polymer degradation behavior.
  • Perform wet chemistry experiments, like residual monomer extractions, Karl Fischer titrations, and acid/base titrations.
  • Collaborate with other teammates within R&D to achieve project goals.
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