Associate Scientist

Beacon Hill; Cambridge (MA); On-site; USD 70,000 - 90,000; Full time

Job summary

A leading company in Cambridge is seeking an Associate Scientist specializing in Cell Therapy. The role involves extensive lab work with a focus on immunology, particularly in NK and CAR-T cell biology. Candidates should have a strong educational background and relevant experience in genomic editing. The position offers a collaborative environment with opportunities for growth and innovation in cell-based therapies.

Qualifications

• Experience in NK cell, TCR-T, and CAR-T cell biology.
• Proficiency in multi-color FACS profiling and cell proliferation assays.

Responsibilities

• Design and implement experiments for CAR-T projects.
• Analyze results and communicate findings within teams.

Skills

Team Spirit

Collaboration

Education

M.S. in Immunology

M.S. in Cell Biology

Tools

FACS Profiling

Electronic Lab Notebooks

Job description

Direct message the job poster from Beacon Hill

Job Title: Associate Scientist, Cell Therapy

Location: 100% on-site in Cambridge

Remote Flexibility: No; 100% Onsite

Contract Term: 6 months to start; 40 hours/week (potential to extend)

Experience required:

• Background in immunology – especially in NK cell, TCR-T and CAR-T cell biology
• This role will involve extensive lab work performing experiments related to building donor criteria for our Allogenic CAR-T program.

As an Immunologist, you will join our Cell Therapy group, leveraging top-notch CRISPR technology to advance cell-based therapies for autoimmune and Immuno-Oncology indications. Your main responsibilities include:

• Designing, implementing, and troubleshooting experiments independently and collaboratively to achieve objectives
• Establishing and performing in vitro/in vivo assays supporting NK cell, TCR-T, and CAR-T projects
• Analyzing and interpreting results using technical and literature knowledge; communicating findings clearly within teams and externally

About You

If you are an Immunologist with a strong interest in genomic editing and cell therapy, our ideal candidate will have a M.S. in Immunology, Cell Biology, or a related field, with solid experience in NK cell, TCR-T, and CAR-T cell biology. We value team players eager to work in a motivated, energetic environment and encourage you to apply.

• Strong team spirit and a can-do attitude are essential; you should thrive in a collaborative environment
• Experience in isolating immune cells from leukopak using magnetic methods, in vitro culture of primary T cells, and performing assays such as T cell killing and cytokine profiling (ELISA or MSD) is required
• Proficiency in multi-color FACS profiling, cell proliferation assays, Incucyte-based assays, and MLR assays is required; experience with cell metabolic assays (e.g., Seahorse Analyzer) is a plus
• Experience with CRISPR gene editing, lentiviral transduction, and AAV insertion in primary T and NK cells
• Experience with Electronic Lab Notebooks (ELN) for detailed protocol and data recording
• Publication record in peer-reviewed journals is a plus

Meet your future team:

The Cell Therapy team is composed of bright, fun, and collaborative individuals passionate about advancing therapies for patients. The team offers exposure to cutting-edge gene and cell therapies, from CRISPR guides to patient support. Your future manager is the Senior Scientist, Cell Therapy. The team mainly works onsite in wet labs; therefore, local candidates or those willing to relocate to Cambridge, MA, are preferred. While wet-lab work is predominant, the team also fosters growth in scientific expertise and career development. Expect a fast-paced, exciting, and collaborative environment focused on skill-building and innovation.