Associate Research Scientist II

Legend Biotech; Piscataway Township (NJ); On-site; USD 80,000 - 100,000; Full time

Job summary

A leading biopharmaceutical company is seeking a talented individual to join their R&D lab, focusing on developing innovative cell therapies for oncology. The role involves conducting experiments in a collaborative environment, requiring a strong background in molecular biology and immunology. Ideal candidates will possess expertise in cell culture and flow cytometry, contributing to cutting-edge cancer treatments.

Qualifications

• B.S. or M.S. in biomedical sciences/cell biology/immunology required.
• Over 5 years with B.S. or 2-5 years with M.S. in related fields.
• Experience with primary T cell-based assays preferred.

Responsibilities

• Assist in developing T cell therapy platforms and perform cell-based immunoassays.
• Culture and characterize genetically modified human T cells.
• Communicate plans and results effectively.

Skills

Multi-color flow cytometry

Data analysis

Mammalian cell culture

Organizational skills

Interpersonal communication

Education

B.S. or M.S. in biomedical sciences

B.S. or M.S. in cell biology

B.S. or M.S. in immunology

Tools

FACSDiva

FlowJo

Job description

From the very beginning, we have been focusing on science. We came together as a team of experts, committed to quality, driven by excellence, and dedicated to experimentation. Despite many challenges, we remained fearless in our research and rigorous in our thinking, pushing ourselves to work harder. What affected us most was the enormous burden patients bear and the difficulties they face, which motivated us to think about what’s next.

We believe it is time to accelerate and expand that transformation. At Legend Biotech, we are excited to bring clinical trials to patients in our pursuit of a cure. While focusing on CAR-T in multiple myeloma, we believe the prospects of cellular therapy extend beyond just one disease or indication. The spark of hope is lit. At Legend Biotech, we are using that hope to ignite the future of CAR-T cell therapy.

Job Description

Role Overview:

Legend Biotech is a clinical-stage biopharmaceutical company focused on discovering and developing novel cell therapies for oncology, immunology, and infectious diseases. We are seeking a talented and motivated candidate to join our R&D cell biology and immunology lab at our US site. The successful candidate will contribute to developing next-generation cell therapies for solid tumor malignancies. They should have a strong background in molecular biology, cell biology, and immunology, and be able to work collaboratively in a cross-functional team, perform experiments, organize and analyze results, communicate effectively, and present findings in team meetings.

Major Responsibilities:

• Assist in developing T cell therapy platforms, perform cell-based immunoassays, including ex vivo antigen-specific T cell isolation and expansion, viral-vector based introduction of TCRs/CARs into human T cells, multi-color flow cytometry, ELISA, ELISPOT assays.
• Culture and characterize genetically modified human T cells and tumor cells, including gene expression and cell functionality testing.
• Plan and execute in vitro functional assays with T cells according to project goals and timelines.
• Communicate plans and results effectively in both oral and written formats.
• Work effectively in a highly dynamic, collaborative team environment.
• Perform other duties as assigned.

Qualifications

Education:

• B.S. or M.S. in biomedical sciences, cell biology, or immunology.

Experience:

• More than 5 years with B.S. or 2-5 years with M.S. in industry or academia in immunology, cell biology, preferably immunotherapy.

Key Capabilities, Knowledge, and Skills:

• Experience with multi-color flow cytometry and data analysis (FACSDiva, FlowJo).
• Experience with primary T cell-based assays preferred.
• Excellent mammalian cell/tissue culture and sterile technique skills required.
• Strong organizational skills and record keeping.
• Self-motivated and adaptable to responsibilities outside initial job scope.
• Ability to work in a fast-paced environment and adjust workload as priorities change.
• Excellent interpersonal, verbal, and written communication skills essential for collaboration.

Additional Information

Legend Biotech USA Inc. is an equal opportunity/affirmative action employer committed to diversity and inclusion. We ensure equal employment opportunity without discrimination or harassment based on race, color, religion, sex, sexual orientation, gender identity, age, disability, national origin, marital status, genetic information, citizenship, veteran status, or any other protected characteristic.

Legend Biotech USA Inc. maintains a drug-free workplace.