Associate Engineer I

amgen; Holly Springs (NC); On-site; USD 65,000 - 90,000; Full time

Benefits offered by this job

Total Rewards Plan

Retirement Savings Plan

Group health, dental and vision

Stock-based incentives

Job summary

Amgen is seeking an Associate Engineer I to provide process development support to manufacturing operations, potentially including mammalian cell culture and lab work to advance Amgen's pipeline. You will apply engineering and scientific principles to improve processes, troubleshoot manufacturing, and develop novel cell culture technologies to increase yield and robustness.

The role offers a competitive Total Rewards Plan and flexible work models where possible, with strong benefits and career

Qualifications

• High school diploma / GED with 6 years scientific experience OR
• Associate’s degree with 4 years of scientific experience OR
• Bachelor’s degree.
• 2 years of experience in a Biotech/Pharma Process Development and/or Manufacturing Support role for drug substance manufacturing.
• Understanding of cell culture processes, influence of raw material attributes, and impact of process deviations to growth and quality attributes.
• Chemical engineering principles for scale up of unit operations from bench to commercial scale.
• Able to apply engineering principles and statistical analysis, including DOE, to solve processing issues and evaluate improvements.
• Chromatography, ultrafiltration and normal flow filtration experience is a plus.
• Excellent written and verbal communication; experience developing and managing training workflows.

Responsibilities

• Provide process development support to manufacturing operations.
• Perform mammalian cell culture and lab activities to support pipeline development.
• Support GMP manufacturing process evaluations and investigations.
• Develop novel mammalian cell culture and next generation technologies to increase yield and robustness.

Skills

Biotech Process Development

Mammalian Cell Culture

DOE / Design of Experiments

Process Scale-Up

Data Analysis

Communication Skills

Troubleshooting Manufacturing

Team Training

Education

Bachelor's degree

Associate's degree

High school diploma / GED

Job description

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

ASSOCIATE ENGINEER I

What you will do

Let’s do this. Let’s change the world. In this vital role you will provide process development support to manufacturing operations and could also perform mammalian cell culture and lab activities to support the commercial development of the Amgen’s pipeline.

• Apply fundamental scientific principles to Biopharmaceutical manufacturing processes (upstream cell culture) in the development of process improvements, facility adaptations, and new process operations.
• Provide technical and on-the-floor support to assist in the troubleshooting of clinical and commercial drug substance manufacturing.
• Support the GMP manufacturing process evaluations and investigations.
• Develop novel mammalian cell culture and next generation technologies to increase yield, process robustness, and enable new unit operations.

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The professional we seek is a person with these qualifications.

Basic Qualifications:

• High school diploma / GED and 6 years of Scientific experience OR
• Associate’s degree and 4 years of Scientific experience OR
• Bachelor’s degree

Preferred Qualifications:

• 2 years of experience in a Biotech/Pharma Process Development and/or Manufacturing Support role for drug substance manufacturing.
• Understanding of cell culture processes, influence of raw material attributes, and impact of process deviations to growth and quality attributes. Harvest and clarification processes used for mammalian cell culture processes.
• Chemical engineering principles for the scale up of unit operations from bench scale to commercial scale.
• Able to apply engineering principles and statistical analysis, including design of experiments, in-order to solve processing issues and evaluate opportunities for process improvements
• Chromatography, ultrafiltration and normal flow filtration operations experience a plus
• Excellent written and verbal communication
• Experience developing and managing team training workflows and strategy.
• Demonstrated ability to work under moderate direction.
• Able to analyze and interpret data
• Be a self-starter with the ability to take on several projects at one time.

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans
• Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.

Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Sponsorship

Sponsorship for this role is not guaranteed.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.