Associate Director / Principal Research Scientist II, Precision Medicine Immunology

University of Georgia- FACS; Waltham (MA); On-site; USD 180,000 - 240,000; Full time

Benefits offered by this job

Paid time off

Medical insurance

401(k)

Long-term incentives

Job summary

AbbVie seeks an experienced translational and biomarker scientist to lead precision medicine activities in its immunology portfolio. You will drive translational strategies, oversee biomarker execution, and coordinate cross-functional teams across internal labs and CROs.

Ideal candidates hold a PhD/MD/PharmD with 6+ years in pharma, with strong immunology expertise, assay development experience, and collaboration skills for regulatory and publication activities.

Qualifications

• PhD/MD/PharmD with 6+ years in pharma or equivalent setting.
• Strong immunology background with publications.
• Leadership in translational science and biomarker development.
• Experience with PD, predictive, and exploratory biomarkers; assays a plus.
• Data management/visualization; collaboration with computational biologists.

Responsibilities

• Lead translational and biomarker strategies for clinical programs.
• Oversee design, conduct, and reporting of biomarker activities.
• Lead asset-specific translational projects in a matrixed environment.
• Coordinate sample management and assay validation with labs/CROs.
• Integrate budgets, timelines, and regulatory needs into strategy.
• Author and review translational medicine sections of docs.
• Lead external scientific collaborations with KOLs.

Skills

Immunology

Translational science

Biomarker development

Assay development

Data analysis

Cross-functional leadership

Communication

Regulatory understanding

Education

PhD/MD/PharmD

MS with 8+ years

Job description

ICompany Description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on LinkedIn, Facebook, Instagram, X and YouTube.

Job Description

The Precision Medicine Immunology group is seeking an experienced translational and biomarker scientist with expertise in immunology to lead the development, planning, execution, and interpretation of precision medicine activities supporting AbbVie's immunology clinical development portfolio.

Key responsibilities include:

• Translational and biomarker strategy: Lead the development and implementation of translational and biomarker strategies for one or more clinical programs, spanning early translational development, mature product life cycle planning, and back-translational research.
• Biomarker execution and interpretation: Oversee the design, conduct, interpretation, and reporting of biomarker activities and data in alignment with development, regulatory, and commercial strategies.
• Cross-functional leadership: Lead asset-specific translational projects and teams within a matrixed environment.
• Operational coordination: Partner with the internal Operations group to coordinate sample management, assay validation at internal laboratories and external CROs, statement-of-work reviews, and data management.
• Program planning and compliance: Collaborate with key stakeholders to incorporate translational budgets, timelines, publication strategies, and regulatory compliance requirements into program strategy.
• Clinical and regulatory documentation: Author and review the translational medicine components of development plans, study protocols, clinical study reports, regulatory submissions, and other clinical and regulatory documents.
• External scientific engagement: Lead scientific collaborations and interactions with therapeutic-area key opinion leaders in partnership with Medical Affairs, Commercial, and other functions.
• Scientific expertise: Maintain current knowledge of the primary scientific literature, state-of-the-art technologies, and emerging concepts in immunology.

Qualifications

• Education and experience: PhD, PharmD, or MD with at least 6 years of relevant experience, or MS with at least 8 years of relevant experience, in the pharmaceutical industry or an equivalent setting. Substantial knowledge of translational and precision medicine science is required. The position level will be determined based on experience.
• Scientific expertise: Strong scientific background in immunology or a related field, supported by a relevant publication record.
• Translational leadership and assay development: Demonstrated leadership in translational science, including the use of pharmacodynamic, predictive, and exploratory biomarkers. Experience developing assays, such as ligand-binding assays, IHC/IF, gene expression profiling, or flow cytometry, is preferred.
• Data analysis and visualization: Familiarity with data management and visualization tools, with experience collaborating with computational biologists to analyze complex clinical trial data sets.
• Therapeutic-area expertise: Expertise in rheumatology is highly desirable.
• Clinical development knowledge: Knowledge of clinical trial methodology, protocol design, regulatory requirements governing clinical trials, companion diagnostics, and development strategy is preferred.
• Program and team management: Ability to manage clinical translational programs and cross-functional teams with moderate supervision.
• Communication and organization: Excellent written and verbal communication skills, with the ability to present results clearly and concisely. Strong organizational skills, attention to detail, effective time management, and adaptability to changing priorities are essential.
• Collaboration: Strong interpersonal and collaboration skills, with the ability to work effectively in a team-oriented, matrixed environment and navigate conflict constructively.

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:

• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
• This job is eligible to participate in our long-term incentive programs.

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company's sole and absolute discretion, consistent with applicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

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