Associate Director/Director, Information Technology

Avalo Therapeutics; Chesterbrook (PA); On-site; USD 120,000 - 150,000; Full time

Job summary

Avalo Therapeutics is seeking an Associate Director/Director of IT to enhance IT capabilities in a regulated biotech environment. This role involves strategic ownership and hands-on execution across various technology domains.

The ideal candidate should possess a deep understanding of IT infrastructure and cybersecurity, along with over 10 years of relevant experience in life sciences. The position requires strong leadership to drive technology solutions that support Avalo's business growth.

Qualifications

• Strong understanding of compliance frameworks like SOX, GxP, FDA.
• Exceptional technical and organizational skills.
• Experience managing MSPs and vendor partnerships.

Responsibilities

• Implement and improve Avalo’s Information Security program.
• Lead implementation of cloud applications and services.
• Ensure compliance with corporate policies and regulations.

Skills

Proactive mindset

Customer-focused

Problem-solving skills

Excellent communication

Ability to manage multiple initiatives

Education

Bachelor’s degree in IT, Computer Science, Engineering or related field

10+ years of progressive IT experience

Tools

Microsoft 365

Microsoft Azure

Cloud infrastructure

Cybersecurity controls

Job description

Associate Director/Director, Information Technology

Chesterbrook, PA

At Avalo (ahh-vah'-low), we are 100% focused on developing treatments for immune-mediated inflammatory diseases with large unmet needs that affect millions worldwide. Our strategy is to develop medicines that target the IL-1β pathway, which is a central driver of the inflammatory process.

We share a commitment to teamwork, passion for science, and dedication to patients suffering from acute and chronic inflammatory disorders. Our collective expertise in discovery, development, and regulatory approvals is evidenced in our strong individual track records of advancing multiple therapeutic programs to successful commercialization.

Position Summary

The Associate Director/Director of IT will be a key contributor in shaping and advancing Avalo’s IT capabilities in a highly regulated biotech/pharmaceutical environment. This role combines strategic ownership with hands‑on execution across infrastructure, cybersecurity, cloud services, digital workplace technologies, and business systems. The ideal candidate brings deep technical expertise in Microsoft 365 and digital workplace technologies, sound judgment, and the ability to partner effectively across scientific and corporate functions to deliver secure, scalable, and fit‑for‑purpose technology solutions that support business growth.

Essential Duties and Responsibilities

• Implement and continuously improve Avalo’s Information Security program ensuring alignment with business objectives and regulatory requirements (SOX, GxP, FDA, and other relevant regulatory standards). Ensure Avalo maintains a strong cyber posture, security first, and cyber aware culture.
• Ensure Avalo’s infrastructure and cloud computing are properly architecture and scaled to support Avalo’s growth.
• Lead the implementation and ongoing optimization of cloud‑based applications, infrastructure, and services to support business growth, scalability, and operational resilience.
• Manage infrastructure including Video/Audio conference systems, and data governance. Ensure infrastructure solutions are compliant with corporate policies/standards and relevant regulations.
• Ensure changes to Avalo Information Systems adhere to the regulatory and compliance requirement.
• Oversee secure endpoint configuration and management in collaboration with Managed Service Provider.
• Keeps up‑to‑date with relevant technology to ensure fit‑for‑purpose, scalable technology implemented to support Avalo’s growth.
• Serve as the system owner and administrator of Avalo business systems ensure technology/systems properly managed and maintained. Partners with business owners ensure the proper control of system access and content management.
• Serve as an escalation point for complex technology issues, ensuring timely resolution and a high‑quality end‑user experience in partnership with internal stakeholders and external service providers.
• Drive user adoption of enterprise technologies by developing practical guidance, training, and support resources that improve employee experience and effective system use.
• Develop and configure solutions from conceptualization to stabilization using various computer platforms.

Required Education and Experience

• Bachelor’s degree in information technology, computer science, engineering, or related field; equivalent experience considered; Master’s degree a plus.
• 10+ years of progressive IT experience, including experience in regulated life sciences, biotech, or pharmaceutical environments.
• Experience supporting cloud infrastructure, digital workplace technologies, business systems, and cybersecurity controls.
• Experience managing MSPs, vendors, and third‑party technology partners.
• Working knowledge of compliance and control frameworks such as SOX, GxP, FDA‑regulated environments, NIST CSF.
• Expertise in Microsoft Azure, cloud architecture, and modern IT infrastructure.
• Familiarity with AI‑enabled workplace tools, governance considerations, and their application in business processes.
• Exceptional problem‑solving skills and willingness to engage in hands‑on technical support.
• Excellent communication and interpersonal skills.

Additional Skills, Knowledge, and/or Abilities

• Proactive, adaptable, and customer‑focused mindset.
• Ability to balance strategic priorities with operational demands.
• Ability to deliver with limited resources and short timeline. And able to manage multiple initiatives at once with good sense of priority setting.
• Strong ownership and sense of urgency in responding to business needs.
• Strong problem and issue resolution skills.
• Technical savvy with ability to quickly master new technology and system.
• Demonstrated technical, organizational, project management skills.

Other Requirements

• Onsite a minimum of 3 days per week.
• Availability to respond to urgent business or system issues outside standard business hours on an as‑needed basis.

About Avalo Therapeutics

Avalo Therapeutics is a clinical stage biotechnology company fully dedicated to developing IL-1β‑based treatments for immune‑mediated inflammatory diseases. Our lead asset, AVTX-009, is in a Phase 2 clinical trial for hidradenitis suppurativa (HS). We’re also exploring additional opportunities to make an impact in prevalent indications that have significant remaining unmet needs. For more information about Avalo, please visit www.avalotx.com.