Associate Director, Chemical Engineering — DS Scale-Up

Nurix Therapeutics; Brisbane (CA); Sur place; USD 190 000 - 217 000; Plein temps

Résumé du poste

Nurix Therapeutics is seeking an experienced Associate Director, Chemical Engineering to lead end‑to‑end DS manufacturing support for bexobrutideg (NX-5948) from late-stage development through commercial launch, including oversight of CDMOs. The Associate Director will work with the CMC team to optimize processes and ensure robust scale‑up.

Based in Brisbane, CA onsite, you will provide technical leadership, drive tech transfer, and coordinate with QA and supply chain to meet regulatory and

Qualifications

• Ph.D. in chemical engineering with 5+ years of industrial late‑phase DS development.
• Extensive GMP DS manufacturing, characterization, process development, scale‑up and validation.
• CDMO management experience including tech transfer activities, QbD and DoE studies.
• In‑depth knowledge of cGMP, ICH, FDA and EMA guidelines.
• Strong collaboration, communication and multitasking; travel up to 25%.

Responsabilités

• Provide leadership to design, develop and optimize scalable routes for DS manufacturing.
• Review CDMO equipment configurations and qualification packages.
• Oversee DS CDMO scale‑up and troubleshooting during batches.
• Lead technology transfer to CDMOs with scale‑up and demonstration of new processes.
• Coordinate with CDMOs, QA, and Global Supply Chain to ensure timely manufacture and release.
• Define engineering strategy for bexobrutideg DS lifecycle and cost of goods.
• Represent Engineering on CMC and cross‑functional teams.
• Mentor scientists and engineers.

Connaissances

Process development

Scale-up engineering

DoE & QbD

CDMO management

Cross-functional collaboration

Regulatory knowledge

Communication skills

Travel readiness

Formation

Ph.D. in chemical engineering

M.S. in chemical engineering with 10+ years experience

B.S. in chemical engineering with 15+ years experience

Outils

Process modeling software

Description du poste

Nurix Therapeutics is seeking an experienced Associate Director, Chemical Engineering to lead end‑to‑end DS manufacturing support for bexobrutideg (NX-5948) from late-stage development through commercial launch, including oversight of CDMOs. The Associate Director will work with the CMC team to optimize processes and ensure robust scale‑up.

Based in Brisbane, CA onsite, you will provide technical leadership, drive tech transfer, and coordinate with QA and supply chain to meet regulatory and