Associate Director, Biostatistics

Centessa Pharmaceuticals; Boston (MA); Remote; USD 130,000 - 190,000; Full time

Job summary

Centessa Pharmaceuticals seeks an Associate Director in Biostatistics to provide strategic statistical leadership across multiple clinical development projects. The ideal candidate will have a Master's degree, significant experience in the pharmaceutical sector, and expertise in statistical methodologies. This remote position with minimal travel requires proficiency in SAS and R, alongside strong communication skills.

Qualifications

• MSc (PhD preferred) in Statistics, Biostatistics or related field.
• Minimum of 6 years of experience in the pharmaceutical industry.
• Experience with regulatory agencies (FDA, EMA) is preferred.

Responsibilities

• Lead biostatistics efforts and oversee clinical development planning.
• Collaborate on clinical development plans for multiple indications.
• Author and review statistical sections for protocols and study reports.

Skills

Statistical methodologies

Communication skills

Statistical modeling

Education

MSc or PhD in Statistics or Biostatistics

Tools

SAS

R

Job description

Join to apply for the Associate Director, Biostatistics role at Centessa Pharmaceuticals

2 days ago Be among the first 25 applicants

Join to apply for the Associate Director, Biostatistics role at Centessa Pharmaceuticals

Company

Centessa Pharmaceuticals plc (Nasdaq: CNTA) new kind of pharmaceutical company with a deconstructed R&D environment that prioritizes data driven decision making led by subject matter experts. Centessa is advancing a portfolio of high conviction programs with strong biological validation.

Company

Centessa Pharmaceuticals plc (Nasdaq: CNTA) new kind of pharmaceutical company with a deconstructed R&D environment that prioritizes data driven decision making led by subject matter experts. Centessa is advancing a portfolio of high conviction programs with strong biological validation.

Our asset-centric model offers a unique R&D logic that has been applied by single asset companies to improve productivity. This operating model has minimal centralized infrastructure, reduced hierarchy, and exclusive focus on data driven capital allocation. Our teams are uniquely incentivized to expeditiously interrogate key scientific hypotheses. We believe the asset-centric model can lead to improved success rates for programs with greater speed and modest costs.

Description Of Role

The Director/Associate Director in Biostatistics will provide statistical leadership in one or more therapeutic areas, oversight of clinical development planning and execution for multiple indications at Centessa.

Key Responsibilities

• Lead biostatistics efforts in a team setting and focus on business priorities
• Collaborate on clinical development plan for one or more molecules to provide biostatistical perspective and insight
• Determine innovative study designs, appropriate statistical tests and methods for evaluating and generating statistical hypotheses to meet study and regulatory requirements
• At study level, author and review statistical sections for protocols, statistical power and sample size estimate, randomization schemes, clinical study reports, and regulatory submission documents
• Lead the planning, organization and analysis of different data sources to enable delivery of the statistical analysis plan and clinical study endpoints for assigned products
• Work with cross-functional team to develop ad hoc analysis plans and ensure analyses are performed appropriately by programming staff
• Lead and guide third-party statistical vendors and contractors in the execution of relevant deliverables (eg, TLFs, SAPs, blinding plans)
• Oversee preparation, conduct, and execution for Data Monitoring Committee meetings
• Maintain expertise in state-of-the-art statistical methodologies and statistical analyses
• Collaborate with Data Management to ensure data integrity and quality
  
  

Qualifications

• MSc (PhD preferred) in Statistics, Biostatistics, or related field
• Minimum of 6 years' experience applying statistical methods in the pharmaceutical industry, with early (Phase 1 and Phase 2) and late (registrational) trial experience highly desired
• Knowledge and experience in neurology and/or oncology therapeutic areas preferred
• Ability to work in a cross-functional matrix environment, and proactively influence teams with innovative clinical development strategy
• Experience of interacting with regulatory agencies, including FDA and EMA, highly desirable
• Demonstrates strong communication skills, both oral and written
• Ability to use SAS and/or R programming languages to perform analyses, conduct statistical modeling, and validate important data derivations
• Hands-on experience working with CDISC standards and programming based on raw datasets, SDTM, and ADaM datasets
• Demonstrates breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes, and create business impact
  
  

Work Location

The Director/Sr. Director in Biostatistics is a remote role based in the US, with infrequent (<10%) travel to our headquarters in Boston, MA.

POSITION: Full-Time, Exempt

EEOC Statement: Centessa Pharmaceuticals believes in a diverse environment and is committed to equal employment opportunity for all its employees and qualified applicants. We do not discriminate in recruitment, hiring, training, promotion, or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Centessa Pharmaceuticals will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Seniority level

• Seniority level

  Mid-Senior level

Employment type

• Employment type

  Full-time

Job function

• Job function

  Research, Analyst, and Information Technology

Referrals increase your chances of interviewing at Centessa Pharmaceuticals by 2x

Sign in to set job alerts for “Associate Director Biostatistics” roles.

Associate Director Biostatistics, Cell Therapy Immunology

Cambridge, MA $119,700 - $270,400 2 weeks ago

Boston, MA
$137,000.00
-
$215,270.00
2 weeks ago

Associate Director, Global Health Economics Lead, Oncology Business Unit

Boston, MA
$153,600.00
-
$241,340.00
1 day ago

Associate Director, Global Health Economics Lead, Oncology Business Unit

Boston, MA
$153,600.00
-
$241,340.00
3 weeks ago

Cambridge, MA
$145,600.00
-
$270,400.00
4 days ago

Cambridge, MA
$147,000.00
-
$212,333.33
1 week ago

Cambridge, MA
$135,100.00
-
$225,100.00
2 weeks ago

Boston, MA
$183,900.00
-
$232,500.00
1 day ago

Boston, MA
$132,200.00
-
$198,300.00
5 days ago

Director or Associate Director, Biostatistics (2 Days Onsite – Boston)

Boston, MA
$126,700.00
-
$160,200.00
2 weeks ago

Cambridge, MA $119,700 - $222,300 2 days ago

Cambridge, MA $138,000 - $185,000 1 month ago

Cambridge, MA $119,700 - $222,300 1 week ago

We’re unlocking community knowledge in a new way. Experts add insights directly into each article, started with the help of AI.