Associate Director, Biometrics — Statistical Strategy & Trials

Ionis Brand; Carlsbad (CA); On-site; USD 165,000 - 223,000; Full time

Benefits offered by this job

Excellent benefits package

Job summary

Ionis Pharmaceuticals, Inc. in Carlsbad, CA, seeks an Associate Director, Biometrics. This senior leadership role leads biostatistics for clinical development, guiding study design, analysis, and interpretation, and oversees CRO activities to ensure scientific rigor.

This position is based in Carlsbad with onsite work preferred; remote options may be considered. Relocation assistance is available for eligible candidates.

Qualifications

• PhD with 5+ years or MS with 8+ years of relevant experience.
• Proficiency in SAS and R.
• Knowledge of CDISC standards and regulatory alignment.
• Strong written and oral communication skills.

Responsibilities

• Provide statistical leadership for assigned clinical development programs/projects, including study design, analysis, interpretation, and development strategy.
• Lead statistical strategy and execution across assigned studies, ensuring scientific rigor, consistency, and alignment with regulatory and industry standards.
• Oversee CRO statistical activities and deliverables, including quality, timelines, and implementation of statistical analysis plans.
• Maintain study documentation of statistical analyses and supportive documents.

Skills

SAS programming

R

Communication skills

Education

PhD in Statistics/Biostatistics or related field

Master’s in Statistics/Biostatistics or related field

Tools

CDISC standards

Job description

Ionis Pharmaceuticals, Inc. in Carlsbad, CA, seeks an Associate Director, Biometrics. This senior leadership role leads biostatistics for clinical development, guiding study design, analysis, and interpretation, and oversees CRO activities to ensure scientific rigor.

This position is based in Carlsbad with onsite work preferred; remote options may be considered. Relocation assistance is available for eligible candidates.