Associate Director, Biologics Manufacturing Ops (External)

Vertex Pharmaceuticals Inc (US); United States; Hybrid; USD 160,000 - 240,000; Full time

Job summary

Vertex Pharmaceuticals Inc (US) seeks an Associate Director, Technical Services to lead the technical execution of biologics drug substance manufacturing at external partners, ensuring compliant, on-time supply. You will drive cross-functional coordination across MSAT, Quality, and manufacturing teams, oversee deviations and CAPAs, and build capabilities within ExM to sustain high performance.

This role emphasizes accountability, rapid issue resolution, and leadership to advance Vertex’s

Qualifications

• BS/BA degree in Biological Sciences, Chemical Engineering, Chemistry or related discipline.
• Requires 10+ years of experience in biologics manufacturing, MSAT, or external manufacturing.
• Demonstrated experience supporting or leading manufacturing execution at a site or external partner.
• Excellent communication and interpersonal skills with ability to influence cross-functional stakeholders.

Responsibilities

• Provide technical leadership for drug substance manufacturing campaigns at external partners.
• Oversee triage, resolution, and documentation of execution-related deviations.
• Lead cross-functional coordination across MSAT, Quality, and manufacturing teams.
• Own process operability and execution robustness at the manufacturing site.
• Drive improvements in yield, cycle time, and overall manufacturing reliability.
• Lead campaign readiness, including CAPAs and process updates.
• Serve as the senior technical interface during operations and drive communication at the site.
• Oversee real-time monitoring of batch and campaign performance and drive timely interventions.
• Escalate complex issues to MSAT with clear technical framing.
• Oversee implementation of approved process and operational changes.
• Build and strengthen Technical Services capability within biologics.

Skills

Biologics manufacturing

cGMP operations

Real-time manufacturing support

Deviations management

Investigations

Change control

Quality systems

MSAT coordination

Leadership

Project management

Cross-functional collaboration

Education

BS/BA in Biological Sciences, Chemical Engineering, Chemistry or related discipline

Advanced degree preferred

Job description

Vertex Pharmaceuticals Inc (US) seeks an Associate Director, Technical Services to lead the technical execution of biologics drug substance manufacturing at external partners, ensuring compliant, on-time supply. You will drive cross-functional coordination across MSAT, Quality, and manufacturing teams, oversee deviations and CAPAs, and build capabilities within ExM to sustain high performance.

This role emphasizes accountability, rapid issue resolution, and leadership to advance Vertex’s