Assoc Scientist, Drug Product and Technology (DPDT)

Regeneron Pharmaceuticals, Inc (USA); United States; On-site; USD 72,000 - 112,000; Full time

Benefits offered by this job

Student Loan Paydown program

Tuition Reimbursement

Family Care Benefits

Relocation Assistance

Inclusion, Culture and Well-Being

Job summary

Regeneron Pharmaceuticals, Inc. seeks an Associate Scientist for the Drug Product Development and Technology (DPDT) team in the CIS group, focused on in-use stability across therapeutic modalities.

The role supports all stages of clinical and commercial development, applying biochemical and biophysical methods to assess stability and compatibility with delivery systems. You will conduct IV compatibility/in-use stability studies, support formulation development, and contribute to study design,

Qualifications

• BS or MS in Chemistry, Biochemistry, Biophysics, Pharmaceutical Sciences, or related field with 0–5 years of industry experience.
• Ability to multitask and work both independently and collaboratively.
• Detail-oriented, self-motivated team player with strong planning, organizational, and oral and written communication skills.

Responsibilities

• Execute IV compatibility/in-use stability studies to support FIH, clinical, and commercial dosing for various modalities including mAbs, bispecifics, proteins, ADCs, and AAVs.
• Support research and technical development in compatibility/in-use stability.
• Perform routine sample analysis to support formulation and product development activities.
• Maintain materials, equipment, and laboratory space for the CIS team.
• With guidance, design and execute CIS studies and other experiments for therapeutic proteins.
• Contribute to study protocols and technical documents for internal use and regulatory filings.
• Apply statistical knowledge to study design and data analysis.
• Present work at group, departmental, and cross-functional meetings.
• Participate in general DPDT lab and instrument maintenance.

Skills

Multitask effectively

Detail-oriented

Team player

Oral and written communication

Education

B.S. or M.S. in Chemistry/Biochemistry/Biophysics/Pharmaceutical Sciences

Tools

Empower

ELN

Job description

At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking an Associate Scientist to join our Drug Product Development and Technology (DPDT) team, on the drug product Compatibility/In-Use Stability (CIS) team, supporting all stages of clinical and commercial drug product development. In this role, you will apply biochemical and biophysical methods to evaluate the stability and compatibility of a diverse set of modalities, such as monoclonal antibodies, bispecific antibodies, proteins, antibody-drug conjugates (ADCs), and adeno-associated viruses (AAVs), with drug delivery systems to enable clinical administration and commercialization. This position offers the opportunity to contribute to a fast-growing, science-driven organization making a meaningful difference to patients worldwide.

When & where:

Shift Requirements: Full-time; Location: On-site in Tarrytown, NY

What you’ll do:

• Execute IV compatibility/in-use stability studies to support first-in-human (FIH), clinical, and commercial drug product dosing for various therapeutic modalities such as monoclonal antibodies, bispecific antibodies, proteins, ADCs, and AAVs
• Support research and technical development in compatibility/in-use stability
• Perform routine sample analysis to support formulation and product development activities
• Maintain materials, equipment, and laboratory space for the compatibility/in-use stability team
• With guidance, design and execute compatibility/in-use stability studies and other experiments to support testing of therapeutic protein molecules
• Contribute to study protocols and technical documents for internal use and regulatory filings
• Apply statistical knowledge to support study design and data analysis
• Present work at group, departmental, and cross-functional meetings
• Participate in general DPDT lab and instrument maintenance

The environment and physical rhythms of this role:

This is a laboratory environment requiring the ability to multitask and work both independently and collaboratively. Detail-oriented, self-motivated teamwork, with strong planning, organizational, and oral and written communication skills, is required.

Must-haves:

• B.S. or M.S. in Chemistry, Biochemistry, Biophysics, Pharmaceutical Sciences, or a related field, with 0-5 years of relevant industry experience
• Ability to multitask and work both independently and collaboratively
• Detail-oriented, self-motivated team player with strong planning, organizational, and oral and written communication skills

Preferred / nice-to-haves:

• Good understanding of protein chemistry and experience with IV admixture compatibility/in-use stability, protein and formulation characterization, and analytical method development
• Experience with biochemical and biophysical techniques for protein characterization, such as particle size (DLS, HIAC, MFI), chromatography (SEC, IEX, RP), gel electrophoresis (CE-SDS, MCE, icIEF), and spectroscopy (UV-Vis)
• Familiarity with common laboratory software (e.g., Empower, ELN)
• Thrive today. Grow tomorrow.

Benefits and perks:

• Student Loan Paydown program
• Tuition Reimbursement
• Family Care Benefits
• Relocation Assistance
• Inclusion, Culture and Well-Being programs (including physical & mental health)

Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits. For additional information about Regeneron benefits in the U.S., please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/. For other locations, additional information will be provided during the recruitment process.

Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

Regeneron is a leading biotechnology company that invents life-transforming medicines for people with serious diseases. Founded and led for over 30 years by physician‑scientists, our unique ability to repeatedly and consistently translate science into medicine has led to nine FDA‑approved treatments and numerous product candidates in development, almost all of which were homegrown in our laboratories. Our medicines and pipeline are designed to help patients with eye diseases, allergic and inflammatory diseases, cancer, cardiovascular and metabolic diseases, neurology, infectious diseases and rare diseases. Regeneron is also proud of award winning culture of innovation, being recognized as a Great Place to Work in 2021, Fast Company’s Best Workplace for Innovators in 2020, and Forbes JUST companies in 2020, among others.

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law.

For jobs in Canada: this posting is for an existing position.

Salary Range (annually) $71,700.00 - $112,300.00