Applied Scientist - Life Sciences AI & Clinical Trials

Amazon Web Services (AWS); Seattle (WA); On-site; USD 143,000 - 193,000; Full time

Job summary

Amazon Development Center U.S., Inc. seeks an Applied Scientist to architect and deploy LLM-based agentic systems for clinical trial operations and drug discovery applications. You will design, train, and evaluate reasoning models, working with senior scientists to ship capabilities used by life sciences teams.

You will advance model customization, rigorously test reliability, and contribute to protein engineering and antibody design projects as the portfolio grows.

Qualifications

• Master's degree or above in a relevant field.
• Applied research with track record of solving complex problems.
• Experience with LLMs, reasoning, and agentic AI.
• Experience building or evaluating agentic systems.
• Publication record at ML or computational biology venues.
• PhD in ML, CS, Computational Biology, or related field; or MS with equivalent applied research.
• Model customization: fine-tuning, RLHF, retrieval augmentation, domain adaptation.
• Programming in Python with PyTorch/JAX.

Responsibilities

• Design, train, fine-tune, and evaluate LLM-based agentic systems that reason over clinical protocols, regulatory standards, and operational workflows
• Build rigorous evaluation harnesses and benchmarks to measure agent reliability, faithfulness, and failure modes in high-stakes domains
• Develop model customization methods (fine-tuning, RLHF, retrieval augmentation, domain adaptation) for better outputs on user data
• Contribute to graph-based and causal modeling approaches for clinical trial operations
• Partner with Life Sciences domain experts, product, and engineering to translate scientific challenges into shipped capabilities
• Own experiments end to end: framing, implementation, evaluation, iteration, hand-off to production
• Publish at top-tier venues where appropriate
• Contribute to drug discovery efforts (protein engineering, antibody design) as opportunities arise

Skills

LLMs & reasoning

Agentic AI

Python

PyTorch

JAX

Research publication

Education

Master's or above in a relevant field

PhD in ML/CS/Computational Biology or MS with equivalent research

MS with equivalent applied research experience

Tools

PyTorch

JAX

Job description

Amazon Development Center U.S., Inc. seeks an Applied Scientist to architect and deploy LLM-based agentic systems for clinical trial operations and drug discovery applications. You will design, train, and evaluate reasoning models, working with senior scientists to ship capabilities used by life sciences teams.

You will advance model customization, rigorously test reliability, and contribute to protein engineering and antibody design projects as the portfolio grows.