Analytical Development Scientist II — Onsite + Equity

Vaxcyte, Inc.; San Diego (CA); On-site; USD 151,000 - 176,000; Full time

Benefits offered by this job

Comprehensive benefits

Equity component

Job summary

Vaxcyte is looking for an energetic and talented individual to join our Analytical Development team. Primary responsibility for the incumbent will be to support the developmental activities currently ongoing in the laboratory as assigned.

Responsibilities include contributing to method development/validation, troubleshooting, and protocol execution, plus supporting transfer activities, data interpretation, and clear documentation across cross-functional teams.

Qualifications

• PhD, MS or BS in Chemistry, Biochemistry, Biology, Pharmaceutical Sciences, or related field; PhD with 2–5 years; MS with 7+ years; BS with 10+ years of relevant industry experience.
• Strong hands-on experience with multiple analytical techniques including colorimetric and fluorescent plate-based assays, UV-Vis, HPLC, CE, SDS-PAGE, icIEF, ELISA, Western Blot and PCR.
• Experience independently driving method development or optimization activities preferred.
• Strong knowledge of analytical chemistry/biochemistry principles with demonstrated application to assay development and control strategies.
• Proven ability to troubleshoot non-routine assay and instrument issues using root-cause analysis and data-driven decision making.

Responsibilities

• Contribute to method development, optimization, and qualification/validation readiness activities.
• Design and execute experiments to evaluate critical method parameters and define system suitability and control strategies.
• Troubleshoot assay and instrument performance issues; identify root causes, implement corrective actions, and document outcomes.
• Support method transfer activities, including protocol preparation, training support, and resolution of transfer issues.
• Support lab management and operations, including sample and inventory tracking.
• Author and revise analytical methods, SOPs, protocols, and technical reports with clear documentation.

Skills

HPLC/UPLC

SDS-PAGE

ELISA

Western Blot

CE

PCR

Data analysis

QC/QA

Analytical dev

Education

PhD (preferred)

MS

BS in Chemistry/Biochemistry

Job description

Vaxcyte is looking for an energetic and talented individual to join our Analytical Development team. Primary responsibility for the incumbent will be to support the developmental activities currently ongoing in the laboratory as assigned.

Responsibilities include contributing to method development/validation, troubleshooting, and protocol execution, plus supporting transfer activities, data interpretation, and clear documentation across cross-functional teams.