Analytical Development Scientist II

Vaxcyte

San Carlos (CA)

On-site

USD 143,000 - 162,000

Full time

9 days ago
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Job summary

Vaxcyte in San Carlos, CA, is seeking a Scientist II, Analytical Development to execute analytical testing and contribute to method development for biologics/vaccine programs. You will perform routine and non-routine analyses with modern techniques, support optimization, and drive investigations with minimal supervision.

The role requires hands-on lab experience, strong data interpretation, and clear documentation.

Qualifications

  • Strong hands-on experience with UV-Vis, HPLC, CE, SDS-PAGE, icIEF, LC, MS, enzyme kinetics and plate-based assays.
  • Experience driving method development or optimization is preferred.
  • Ability to produce inspection-ready documentation and robust data interpretation.

Responsibilities

  • Contribute to method development, optimization, and qualification/validation readiness activities.
  • Design and execute experiments to evaluate critical method parameters and define appropriate system suitability and control strategies.
  • Troubleshoot assay and instrument performance issues with root-cause analysis and corrective actions.
  • Support and/or execute method transfer activities, including protocol preparation and training support.
  • Author and revise analytical methods, SOPs, protocols, and technical reports for internal review.

Skills

UV-Vis
HPLC
CE
SDS-PAGE
icIEF
Mass Spectrometry
Enzyme kinetics
Plate-based assays
ELISA
Western blot
PCR

Education

PhD in Chemistry/ Biochemistry/ Biology/ Pharmaceutical Sciences
MS in Chemistry/ Biochemistry/ Biology/ Pharmaceutical Sciences
BS/BA in a related field

Tools

Analytical software

Job description

Vaxcyte in San Carlos, CA, is seeking a Scientist II, Analytical Development to execute analytical testing and contribute to method development for biologics/vaccine programs. You will perform routine and non-routine analyses with modern techniques, support optimization, and drive investigations with minimal supervision.

The role requires hands-on lab experience, strong data interpretation, and clear documentation.

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