AI-Driven Computational Biologist, Pharma R&D

Tempus AI, Inc.; Boston (MA); On-site; USD 90,000 - 150,000; Full time

Job summary

Tempus AI, Inc. seeks a Scientist II to join the Computational Biology, Pharma R&D team, focused on integrating large-scale molecular and clinical datasets to drive drug discovery and development.

You will collaborate with pharmaceutical partners, apply robust statistics and machine learning, and build scalable research tools leveraging AI, LLMs, and foundation models. The role demands strong coding, collaboration, and translational science passion.

Qualifications

• PhD in Computational Biology, Bioinformatics, Biostatistics, Machine Learning, or a related field (or master’s degree with 3+ years).
• Proficiency in R and/or Python, including common libraries for computational biology and scientific computing.
• Experience with machine learning, LLM-based coding assistants, and agentic frameworks for biological/clinical research.
• Adherence to good software engineering practices (version control, modular code, documentation).
• Experience with SQL and large relational databases.
• Strong grounding in statistics and data analysis, including study design considerations and interpretation of real-world clinical data.
• Scientific knowledge in cancer biology, immunology, or human disease mechanisms.

Responsibilities

• Pharma collaboration & strategy: partner with pharmaceutical collaborators to execute computational research plans.
• Computational analysis: integrate genomic, transcriptomic, imaging, and clinical data to derive insights.
• AI & LLM innovation: apply foundation models and AI tools to accelerate workflows.
• Method development: adapt new methods for real-world, clinical, and omics datasets.
• Cross-functional collaboration: work with Research, Clinical, Data Science, and Engineering teams to refine analyses.
• Scientific communication: present results to technical and non-technical stakeholders.

Skills

R and Python proficiency

ML/LLM tooling

Statistics & study design

Communication skills

Adaptability in fast-paced env

Education

PhD in Computational Biology/Bioinformatics/ Biostatistics/ ML

Master’s + 3+ years experience

Tools

SQL

Git / version control

LLM tooling (Claude Code/Codex)

Job description

Tempus AI, Inc. seeks a Scientist II to join the Computational Biology, Pharma R&D team, focused on integrating large-scale molecular and clinical datasets to drive drug discovery and development.

You will collaborate with pharmaceutical partners, apply robust statistics and machine learning, and build scalable research tools leveraging AI, LLMs, and foundation models. The role demands strong coding, collaboration, and translational science passion.