Accounting Manager

Brave; San Francisco (CA); Hybrid; USD 125,000 - 145,000; Full time

Job summary

Braveheart Bio is a clinical-stage biopharmaceutical company advancing therapies for hypertrophic cardiomyopathy. The Accounting Manager will own day-to-day accounting operations, support month-end close, and prepare clinical accruals for a fast-moving biotech environment.

The role reports to the Senior Director, Controller, and partners with finance, clinical operations, and external vendors to scale the business while strengthening internal controls and financial reporting.

Qualifications

• 5+ years of progressive finance and accounting experience.
• Bachelor’s degree in accounting or related field.
• US GAAP knowledge including R&D accruals and clinical trial accounting.
• SOX/internal controls knowledge and cross-functional alignment.
• Public company audits experience with Big 4 or national firms.
• Strong communication and collaboration skills.

Responsibilities

• Support monthly close and FP&A budget-to-actual reporting.
• Review journal entries and reconciliations; mentor staff.
• Own clinical trial accruals with CROs and vendors.
• Implement policies and internal controls; streamline processes.
• Support audits, reviews, and system implementations.

Skills

5+ years finance

US GAAP knowledge

Excel proficiency

Public company audits

SOX internal controls

Cross-functional collaboration

Fast-paced environment

Ambiguity tolerance

Hands-on mindset

Big 4 audits experience

CPA preferred

NetSuite experience

Education

Bachelor’s degree in accounting or related field

Tools

NetSuite

Job description

Braveheart Bio is a clinical-stage biopharmaceutical company focused on developing therapies for patients with hypertrophic cardiomyopathy (HCM) and other serious cardiovascular diseases. Our lead product candidate, BHB-1893, is a next-generation oral small-molecule cardiac myosin inhibitor (CMI) being developed for the treatment of obstructive HCM (oHCM) and non-obstructive HCM (nHCM). Braveheart’s goal is to improve the treatment options for these patients by enhancing speed of onset, depth of gradient response, systolic safety, reversibility and reducing prescribing complexity.

With a proven leadership team, a strong financial foundation, and a high-value late-stage asset, Braveheart Bio represents an outstanding opportunity for ambitious, mission-driven professionals to make a tangible impact in a high-profile and rapidly evolving therapeutic area.

The role:

The Accounting Manager will own day-to-day accounting operations, support the month-end close process, and prepare clinical trial accruals for our fast-moving clinical-stage biotechnology company. Reporting to the Senior Director, Controller, this hands-on role will support internal controls, financial reporting, system implementations, and collaboration with finance, clinical operations, external vendors, and other cross-functional partners as Braveheart Bio continues to scale.

Key responsibilities:

• Support the monthly accounting close process, ensuring a timely, accurate close within external and internal reporting deadlines. Support FP&A budget to actual reporting.
• Review journal entries and reconciliations prepared by accounting team members. Supervise, mentor, and develop junior accounting staff.
• Own clinical trial accrual preparation including review of clinical contracts, CRO reports, patient costs, site costs, and invoices; liaise directly with internal stakeholders and clinical vendors to ensure accruals are complete, accurate, and timely.
• Implement policies and procedures for accounting activities and functions. Maintain internal controls in areas of responsibility. Improve and streamline processes where appropriate.
• Support annual audits, quarterly financial reviews, and internal controls testing. Support system implementations and other projects as needed.
• Promote a culture of collaboration, inclusion, execution excellence, effective communication and cross-functional problem-solving as a key member of a high-performing team.

Required experience & skills:

• 5+ years of progressive finance and accounting experience, with publicly traded, pre-IPO, or clinical stage biotech/life sciences companies preferred.
• Bachelor’s degree in accounting or related field.
• Deep technical accounting knowledge (US GAAP), including R&D accruals and clinical trial accounting.
• Advanced proficiency in Microsoft Excel (XLOOKUP, INDEX/MATCH, etc.)
• Strong knowledge of public company requirements, internal controls (SOX), and cross-functional alignment.
• Experience supporting Big 4 or national firm audits.
• Excellent judgment, high integrity, and the ability to operate in a fast-moving environment.
• Strong written and verbal communication skills with a collaborative, team-oriented approach.
• Ability to thrive in a fast-paced, dynamic environment and remain comfortable with change and ambiguity.
• Flexible, proactive, and hands‑on mindset with a roll‑up‑your‑sleeves, can‑do attitude.

Preferred experience & skills:

• CPA license preferred.
• Public accounting experience preferred.
• Experience with NetSuite preferred.

Base Salary Range: $125,000 - $145,000

We are an equal opportunity employer.

We are committed to inclusion and diversity, and we do not discriminate on the basis of race, gender, religion, gender, sexual orientation, age, color, marital status, veteran status, disability status, national origin, or any characteristic protected under applicable law.

Braveheart participates in the federal E‑Verify program to confirm employment authorization for all new hires.

To learn more about E-Verify please review this poster.