3rd shift Manufacturing Supervisor (Biotech)

Astrix; Chicago (IL); On-site; USD 93,000 - 104,000; Full time

Job summary

A leading company in the biotech industry is seeking a 3rd Shift Manufacturing Supervisor to oversee production processes, ensure product quality, and manage team performance. Candidates should possess a relevant degree and significant industry experience, focusing on quality management and team engagement in a fast-paced environment.

Benefits

Medical insurance

Vision insurance

Qualifications

• Experience with biotechnology operations such as aseptic filtration systems.
• Supervisory experience is preferred.
• Ability to understand technical information and procedures in English.

Responsibilities

• Ensure quality data is maintained while meeting production goals.
• Monitor product quality using PLC controls and HMI interfacing.
• Complete Batch Records and other cGMP documentation.

Skills

Problem-Solving

Multitasking

Team Engagement

Quality Monitoring

Communication Skills

Education

Bachelor's degree in engineering, pharmaceuticals, or related life sciences

Master's degree in engineering, pharmaceuticals, or related life sciences

5–10 years of industry experience

Tools

PCR

LIMS

SAP

Job description

3rd shift Manufacturing Supervisor (Biotech)

3rd shift Manufacturing Supervisor (Biotech)

1 week ago Be among the first 25 applicants

This range is provided by Astrix. Your actual pay will be based on your skills and experience — talk with your recruiter to learn more.

Base pay range

$93,000.00/yr - $104,000.00/yr

Direct message the job poster from Astrix

Scientific and technical staffing leader connecting top talent with industry-leading companies

Hours: 3rd shift10:00pm – 6:30am

Essential Job Functions:

• Execute and Delegate: Execute and effectively delegate work instructions, production specifications, and standard operating procedures (SOPs) to perform key responsibilities. Ensure quality data is maintained while meeting production goals, timelines, and minimizing downtime/delays. Perform work instructions with minimal supervision, including but not limited to:
• Weighing and dispensing materials.
• Media and buffer preparation.
• Operating filtration systems (e.g., dead-end filtration, depth filtration, tangential flow filtration).
• Inoculating, fermenting, harvesting, and homogenizing cytokine cells.
• Setting up and operating chromatography columns.
• Performing aseptic final filtration of intermediates and drug substances.
• Quality Monitoring: Monitor product quality using PLC controls, HMI interfacing, integrity testing, and in-process testing (e.g., pH, conductivity, spectroscopy). Routinely adjust controls and interact with HMI interfaces to ensure smooth equipment operation. Diagnose and troubleshoot equipment and manufacturing processes.
• Multitasking and Problem-Solving: Possess the ability to multitask, solve problems, and formulate action plans based on real data and experience. Thrive in a fast-paced, team-oriented environment.
• Training and Development: Train diverse team members, ensuring employee training is current and meets job standards.
• Team Engagement: Build team engagement through regular 1:1 meetings, goal-setting, performance reviews, and providing growth opportunities. Offer coaching, counseling, development, discipline, and recognition. Manage timecards and attendance.
• Safety Prioritization: Foster a safety-first environment by enforcing proper PPE usage, ensuring hazardous materials (e.g., buffers, chemicals) are handled and disposed of according to EHS guidelines, and maintaining clean manufacturing areas
• Cleanroom Maintenance: Follow daily and weekly cleaning routines for cleanrooms and equipment to maintain required conditions for cleanroom manufacturing. Perform routine area checks and coordinate with relevant personnel for resolution.
• Inventory Management: Verify raw materials and commodities. Accurately enter inventory data into MES daily, perform routine inventory counts and adjustments, and request raw materials and commodities as needed.
• Documentation: Complete Batch Records and other cGMP documentation accurately and promptly. Perform daily documentation reviews and approvals. Assist with Change Control, CAPA, and Deviation/Investigation documentation.
• Incident Reporting: Report nonconformances or events to the manager and gather requested evidence during the shift.
• Technology Transfer: Assist in transferring technology from Process Development to cGMP Manufacturing. Participate in qualification and validation activities.
• Document Authoring: Author and review SOPs and other documents to integrate cGMPs and improve process efficiency.
• Process Monitoring: Perform process monitoring using databases, documents, and spreadsheets to meet business reporting requirements.
• Continuous Improvement: Propose improvements and efficiencies to reduce waste and increase production while adhering to quality standards.
• Policy Compliance: Comply with all safety, cGMP, and company policies, practices, and procedures

Education:

• Bachelor’s degree in engineering, pharmaceuticals, or related life sciences with at least five years of experience; or
• Master’s degree in engineering, pharmaceuticals, or related life sciences with at least two years of experience; or
• An equivalent of 5–10 years of industry experience is required.
• Upstream and downstream manufacturing or biotechnology experience is preferred. Supervisory experience is also preferred.

Special Skills:

Language:

• Basic verbal and written communication skills in English.
• Ability to understand technical information, procedures, batch records, and other documents in English.
• Excellent interpersonal skills for effective communication with peers, supervisors, and supporting departments.

Technical Proficiency:

• Proficiency with systems such as Delta, PCR, POMS, LIMS, SAP, etc.
• Knowledge of GMP, safety requirements, and the current Code of Federal Regulations (CFRs).
• Familiarity with lean and continuous improvement tools (e.g., 5 Why, RCFA, Six Sigma).
• Experience with biotechnology operations such as aseptic filtration systems, filter integrity testing, fermentation, chromatography columns, mixing systems, and weighing scales

Seniority level

• Seniority level

  Mid-Senior level

Employment type

• Employment type

  Full-time

Job function

• Job function

  Manufacturing and Science

• Industries

  Pharmaceutical Manufacturing and Biotechnology Research

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Inferred from the description for this job

Medical insurance

Vision insurance

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