2027 Spring Co op Bioanalytics Cambridge MA

Sanofi; Cambridge (MA); On-site; USD 65,000 - 92,000; Full time

Job summary

Sanofi's Translational Medicine Unit (TMU) LabSci seeks a co-op to gain hands-on experience in developing PK/PD bioanalytical LC-MS assays for non-clinical studies.

You will learn to qualify assays, perform sample preparation and analyze PK data while contributing to drug development and collaborating with multidisciplinary teams in Cambridge.

Qualifications

• Pursuing a PhD in biochemistry/biotechnology/pharmaceutical sciences with expected graduation by Dec 2028.
• Must be legally authorized to work in the U.S. without sponsorship.
• Enrolled in an accredited college/university for duration of co-op/internship.
• Willingness to relocate to Cambridge, MA and work 40 hrs/week, Mon-Fri.

Responsibilities

• Design, develop and qualify PK LC-MS assays for preclinical biologics/AOCs.
• Develop sample preparation methods such as protein precipitation and SPE.
• Utilize LC-MS/MS or LC-HRMS for intact protein or bottom-up analysis.
• Characterize PK profiles and integrity of constructs.
• Analyze samples to support PK/PD analyses in discovery and preclinical studies.
• Present bioanalytical results and participate in scientific discussions.

Skills

PK/PD concepts

Mass spectrometry

Protein analysis

Bioanalytical sample prep

AI tools for drug discovery

Education

PhD candidate in biochemistry/biotechnology/pharmaceutical sciences

Tools

TOF/Orbitrap mass spectrometry

Triple quadrupole mass spectrometry

Protein analysis platforms (Thermo/Waters/Sciex)

Job description

About the Job

Looking to launch your career at the cutting edge of healthcare? Join Sanofi for a chance to develop with mentoring and guidance from inspirational leaders while helping to make an impact on the lives of countless people worldwide. The non‑clinical bioanalysis team within the Translational Medicine Unit (TMU) LabSci department at Sanofi is searching for a co‑op to join their team. This team develops bioanalytical assays to understand pharmacokinetics (PK) and pharmacodynamics (PD) and interacts with allied functions for first‑in‑human (FIH) dose predictions. This co‑op will be a part of the dynamic team and work on developing novel LC‑MS‑based methods to support non‑clinical PK/PD. Ready to grow your skills while helping shape the future of healthcare? At Sanofi, you’ll be empowered to learn, ask questions, and bring your ideas to life – all while supported by inspiring mentors and collaborative teams.

About Sanofi

We’re an R&D‑driven, AI‑powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people’s lives.

Main Responsibilities

• With supervision, design, develop and fit‑for‑purpose qualify PK LC‑MS assays in preclinical setting for biologics and AOCs (Antibody oligonucleotide conjugates).
• Develop sample preparation approaches such as protein precipitation, solid phase extraction, Immunoprecipitation, enzymatic digestions etc.
• Develop LC‑MS/MS and LC‑HRMS for intact protein analysis, middle‑up approach or bottom‑up approach.
• Use these methods to characterize pharmacokinetic profile of constructs, including integrity analysis.
• Analyze samples to support pharmacokinetic and pharmacodynamic analysis for discovery and preclinical studies.
• Report and discuss bioanalytical and biomarker results with integrative knowledge of how the data contributes to the drug development process.
• Actively contribute to scientific discussions.

Basic Qualifications

• Currently pursuing aPhD degree in biochemistry, biotechnology, pharmaceutical sciences or related health sciences at an accredited college or university, with an expected graduation date no later than Dec2028.
• Must be permanently authorized to work in the U.S. and not require sponsorship of an employment visa (e.g., H‑1B or green card) at the time of application or in the future.
• Students currently on CPT, OPT, or STEM OPT usually require future sponsorship for long term employment and do not meet the requirements for this program unless eligible for an alternative long‑term status that does not require company sponsorship.
• Must be enrolled in an accredited college or university throughout the duration of the co‑op/internship.
• Must be able to relocate to the office location and work40hrs/week, Monday‑Friday, for the full duration of the co‑op/internship.
• Knowledge of pharmacokinetics (PK) and pharmacodynamics (PD) concepts and their role in drug development.
• Expertise in at least one mass spectrometry platform: either high‑resolution mass spectrometry (time‑of‑flight or Orbitrap) or triple quadrupole mass spectrometry.
• Good understanding of protein analysis on at least one of the following platforms: Thermo, Waters, or Sciex.
• Experience with at least one extraction technique for protein quantitation in biological matrices (plasma and/or tissues), such as protein precipitation, solid phase extraction, immunoprecipitation, or enzymatic digestion.
• Knowledge of proteomics tools, including protein database queries and protein sequence analysis.

Preferred Qualifications

• Experience utilizing (AI) artificial intelligence tools for drug discovery and development.
• Scientific curiosity, appetite for teamwork, and strong problem‑solving skills.
• Excellent organizational and documentation skills.
• Good written and oral communication skills along with the ability to work collaboratively in a team setting.
• Demonstrated ability to work independently to develop and/or qualify bioanalytical assays.

Why Choose Us

Bring the miracles of science to life alongside a supportive, future focused team. Stretch your skills through apprenticeships, internships, graduate programs, and international experiences that grow with you. Learn from inspiring mentors and collaborative teams while contributing to real projects that shape the future of healthcare. Build your future with access to the latest tools, digital innovation, and continuous learning that keep you ahead of the curve.

Compensation

The salary for this position is $57 hourly. All compensation will be determined commensurate with demonstrated experience.

Equal Opportunity

Sanofi US endeavours to make our career center accessible to any and all users.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity employers committed to a culturally inclusive workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

We are an R&D driven, AI‑powered biopharma company committed to improving people’s lives and creating compelling growth. Our team is guided by one purpose: we chase the miracles of science to improve people’s lives. We want to build a healthier, more resilient world, and turn the impossible into the possible by discovering, developing, and delivering medicines and vaccines for millions of people around the world. Discover more about us visiting www.sanofi.com or via our movie We are Sanofi Start a career that makes a difference. Reinvention is in our DNA. It’s what drove our evolution from a small French enterprise to one of the world’s leading biopharma companies. Whether it’s using AI to shorten drug‑discovery times or building trust in healthcare, you could be helping our teams make life better for patients, partners, and communities. This is where you grow your career. We open the door for you to explore new opportunities, push your limits, and connect with people who are driven by a shared purpose: we chase the miracles of science to improve people’s lives.