2027 Co-op Genome Engineering & Transgenic Model Development

Regeneron Pharmaceuticals; Tarrytown (GA); On-site; USD 25,000 - 70,000; Full time

Job summary

Regeneron Pharmaceuticals, in Tarrytown, NY, invites applications for a 2027 Co-op in Genome Engineering & Transgenic Model Development to advance VelociGene activities. The role focuses on validating gene-editing tools in cells and mouse models, with hands-on DNA techniques and protein analyses.

You will collaborate with scientists to optimize an editing platform, screen variants, and apply structure-prediction methods, while maintaining rigorous documentation and safety standards.

Qualifications

• Must be enrolled in, or accepted to, an academic program pursuing an Undergraduate or Graduate degree.
• Must be able to commit to 40 hours per week from January-August, May/June-December, or August-December.
• GPA of 3.0 or higher preferred.
• Demonstrated leadership in activities, clubs, sports, work, or community preferred.

Responsibilities

• Contribute to the development of a proprietary gene-editing enhancement platform designed for both in vitro and in vivo use.
• Screen engineered protein variants using a fluorescence-based reporter assay to identify compact, enhanced versions that retain function.
• Apply computational structure-prediction tools to help design engineered protein variants.
• Evaluate a modified, DNA-nicking version of Cas9 to assess whether it reduces unwanted genomic effects while preserving editing efficiency.
• Perform basic molecular biology techniques such as PCR, cloning and subcloning, and western blotting.
• Perform mammalian cell culture techniques, including sterile technique, passaging, and transfection or electroporation.
• Work with viral vectors and flow cytometry methods.
• Document experimental procedures and results using tools such as Excel and Prism, and collaborate with scientists across the VelociGene team.

Skills

Molecular biology

PCR

Cloning

Cell culture

Flow cytometry

Western blotting

Fluorescence-based reporter assay

Computational structure prediction

Collaboration

Education

Undergraduate or Graduate degree pursuit

Returning to school after position

Tools

Excel

Prism

Job description

At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. Regeneron is currently seeking a 2027 Co-op in Genome Engineering & Transgenic Model Development to join our VelociGene team, which develops next-generation gene-editing tools to improve the precision and safety of genome engineering for cell lines, mouse models, and future therapeutics.

These positions offer the opportunity to contribute to a fast-growing, science-driven organization making a meaningful difference to patients worldwide.

When & where:

Location: Tarrytown, NY

Timeframe: Our Co-op positions are full-time and onsite from January-August (Spring-Summer), May/June-December (Summer-Fall), and August-December (Fall).

Pay : Intern and Co-op pay ranges are determined by level of education (year in school) and degree program. The hourly rate range for these locations is: $17.90-$50.90 per hour.

What you’ll do:

• Contribute to the development of a proprietary gene-editing enhancement platform designed for both in vitro and in vivo use
• Screen engineered protein variants using a fluorescence-based reporter assay to identify compact, enhanced versions that retain function
• Apply computational structure-prediction tools to help design engineered protein variants
• Evaluate a modified, DNA-nicking version of Cas9 to assess whether it reduces unwanted genomic effects while preserving editing efficiency
• Perform basic molecular biology techniques such as polymerase chain reaction (PCR), cloning and subcloning, and western blotting
• Perform mammalian cell culture techniques, including sterile technique, passaging, and transfection or electroporation
• Work with viral vectors and flow cytometry methods
• Document experimental procedures and results using tools such as Excel and Prism, and collaborate with scientists across the VelociGene team

Relevant majors: Biology, Biomedical Engineering, Molecular Biology, Genetics, Chemistry

Let’s find out if we’re a fit :

• Must be enrolled in, or accepted to, an academic program pursuing an Undergraduate or Graduate degree (and be returning to school the semester following the position or graduating after the position)
• Must be able to commit to 40 hours per week from January-August, May/June-December, or August-December
• Demonstrated leadership in areas such as campus activities, clubs, sports, current or previous work, or within the community preferred
• Cumulative GPA of 3.0 or higher preferred

We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

Where necessary, we disclose salary ranges for roles in all countries in which we operate. The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits. Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits. For additional information about Regeneron benefits in the U.S., please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/. For other locations, additional information will be provided during the recruitment process.

Please be advised that at Regeneron, we believe we do our best work when we are together. For that reason, many roles are required to be performed on-site.

As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where the position is based. The purpose of such checks is to verify certain information prior to the commencement of employment such as identity, right to work and educational qualifications.

For jobs in Canada: this posting is for an existing position.