Translational Genomics & Functional Validation Scientist

Mikrogen; Turkey; On-site; TRY 90,000 - 130,000; Full time

Job summary

Mikrogen Genetic Diagnosis Center is seeking a PhD-level researcher to join the team of its Translational Genomics and Advanced Therapeutic Technologies Leading R&D Laboratory under the TÜBİTAK 1515 Programme.

The researcher will focus on the functional characterization of genetic variants, disease mechanisms and candidate molecular targets, linking genomic findings with experimental evidence through cell-based and molecular assays.

Qualifications

• PhD in Molecular Biology and Genetics or related field.
• Strong hands-on experience in functional genomics and cellular assays.
• Experience in experimental investigation of genetic variants or disease mechanisms.
• Proficiency with qPCR, RT-PCR, Western blotting, immunofluorescence, flow cytometry and cell culture.
• Experience in mammalian cell culture and experimental model development.
• Ability to independently design experiments, interpret results and troubleshoot workflows.
• Strong understanding of gene function, molecular pathways and genotype–phenotype relationships.
• Scientific publication record.

Responsibilities

• Designing and performing functional studies for candidate genetic variants.
• Investigating molecular and cellular consequences of disease-associated variants.
• Developing and applying cell-based functional assays.
• Establishing experimental models for rare and genetic diseases.
• Contributing to variant interpretation and reclassification, including VUS when relevant.
• Collaborating with clinical genomics and bioinformatics teams.
• Contributing to national and international R&D projects and publications.

Skills

Molecular biology

Functional genomics

Cell biology

Genotype–phenotype relations

Scientific publications

Education

PhD in Molecular Biology and Genetics, Cell Biology or related field

Tools

qPCR

RT-PCR

Western blotting

Immunofluorescence

Flow cytometry

Cell culture

Job description

Mikrogen Genetic Diagnosis Center is seeking a PhD-level researcher to join the team of its Translational Genomics and Advanced Therapeutic Technologies Leading R&D Laboratory under the TÜBİTAK 1515 Programme.

The researcher will focus on the functional characterization of genetic variants, disease mechanisms and candidate molecular targets, linking genomic findings with experimental evidence through cell-based and molecular assays.