Senior Staff Program Manager

Illumina; Singapore; On-site; SGD 200,000 - 260,000; Full time

Job summary

Illumina is seeking an experienced Program Manager to lead its data platform initiative. You will coordinate across engineering and bioinformatics teams, shaping scope, schedule, and budget while communicating status to senior leadership.

The role emphasizes scaled Agile practices, AI-driven development, and governance in a managed software quality environment. Experience in genomics is highly valued.

Qualifications

• 12+ years of proven experience leading and delivering multiple complex software projects.
• 5+ years in a regulated environment.
• Ability to communicate across all levels of the organization.
• Strong understanding of software development processes and project planning/execution.
• Excellent written and verbal communication, with ability to present to senior leaders.
• Experience with genomics or multiomics data is a strong plus and quick domain learning ability.

Responsibilities

• Lead major data platform initiatives spanning multiple engineering and product teams.
• Collaborate with architects, product managers, and engineers on scope, tradeoffs, and technical decisions.
• Drive a cross-functional Core Team to deliver program commitments.
• Create and manage software project plans including scope, schedule, staffing, quality, risk, and dependencies.
• Align stakeholders with business objectives and prioritization for successful delivery.
• Lead projects that rely on AI tools and ensure alignment with user needs.
• Operate in an agile environment and manage progress with dashboards and reviews.
• Identify and resolve issues, manage risks, and drive governance meetings for resources.

Skills

Leadership

Stakeholder management

Program management

Agile / SAFe

Communication

Risk management

Regulated environment experience

Domain knowledge (genomics/bioinfo)

Presentation to senior leaders

Cross-functional collaboration

Education

Bachelor’s degree in Computer Science, Engineering, or related field

Tools

AWS

GCP

Azure

Python

SQL

Job description

What if the work you did every day could impact the lives of people you know? Or all of humanity? At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients. Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible.

Position Summary:

In this role you will be the program manager for Illumina’s data platform. This is a highly complex, visible role sitting at the intersection of many teams. You will tackle challenging problems and be responsible for delivering high profile projects across multiple software and bio-informatics teams to ensure goals and commitments are met. You will interface with other technology teams and senior leadership to establish scope, schedule, and cost as well as communicating status, issues, and risks. Additionally, you will be part of a team integrating scaled agile software development processes and AI driven development in a managed SW quality environment.

Responsibilities:

• Lead and own major data platform initiatives that span multiple engineering and product teams
• Work closely with architects, product managers, and engineers on scope, tradeoffs, and technical decisions and to challenge assumptions, spot integration gaps early, and make credible calls on sequencing and risk.
• Drive a cross-functional leadership team (a.k.a. Core Team) in successfully delivering program commitments.
• Create and execute software project plans (scope, schedule, staffing plans, quality, risk management, budget, dependencies, and procurement) and revise them appropriately to meet changing needs and requirements.
• Work effectively with stakeholders to ensure alignment with business objectives, correct prioritization, and successful project delivery.
• Lead projects that heavily rely on AI tools and ensure alignment between user needs and development outputs.
• Lead projects in an agile environment.
• Track project progress to plan through metrics and make corrections and/or reset expectations as needed.
• Lead senior management reviews and governance meetings for your program’s pool of resources.
• Identify, resolve and/or escape issues as appropriate.
• Facilitate tradeoff decisions and removes obstacles.
• Continuously analyze and manage program risks to enable successful project completion.
• Define and optimize project and program management and overall software development processes, methodologies, and tools to improve organizational efficiency and effectiveness.

Listed responsibilities are an essential, but not exhaustive list, of the usual duties associated with the position. Changes to individual responsibilities may occur due to business needs.

Requirements:

• 12 or more years proven experience leading and delivering multiple complex software application projects.
• 5 or more years of recent experience working in a regulated environment.
• Must be able to work independently and communicate across all levels of the organization.
• Strong understanding of the software development processes and project planning/execution skills that include estimating and scheduling.
• Polished communication skills and able to communicate with confidence, clarity, and focus.
• Ability to communicate software concepts and considerations to non-software professionals.
• Comfortable and experienced presenting to senior leaders.
• Experience with genomics or multiomics data is a strong plus, and a strong ability to learn the domain is required if you don’t yet have it.
• Demonstrated business judgement navigating complex program challenges to deliver enterprise-scale software successfully according to contract.
• Excellent leadership skills, you understand how to own the outcome.
• Demonstrated ability to work in a matrix environment, and ability to influence at all levels.
• Demonstrated success championing and delivering improvements to the software development and program management processes of a growing organization.

All listed requirements are deemed as essential functions to this position; however, business conditions may require reasonable accommodations for additional task and responsibilities.

Preferred Skills & Experience:

• Typically requires a minimum of 12 years of related experience
• Bachelor’s degree (or higher) in Computer Science, Math, Engineering, Science, or a related technical discipline
• Experience delivering programs on cloud hyperscalers (AWS, GCP, Azure) and/or life sciences software
• Experience working in an AI-native software development environment
• Experience with data pipeline and workflow orchestration systems
• Experience with population-scale genomics, biobank programs, or other large scientific data platforms
• Background in genomics, bioinformatics, or computational biology
• Coding or data analysis experience (Python, SQL, R) sufficient to prototype, validate, and reason about data quality
• Partner- or customer-facing delivery experience on a complex technical engagement
• Experience working with life sciences quality management systems

We are a company deeply rooted in belonging, promoting an inclusive environment where employees feel valued and empowered to contribute to our mission. Built on a strong foundation, Illumina has always prioritized openness, collaboration, and seeking alternative perspectives to propel innovation in genomics. We are proud to confirm a zero-net gap in pay, regardless of gender, ethnicity, or race. We also have several Employee Resource Groups (ERG) that deliver career development experiences, increase cultural awareness, and offer opportunities to engage in social responsibility.

We are proud to be an equal opportunity employer committed to providing employment opportunity regardless of sex, race, creed, color, gender, religion, marital status, domestic partner status, age, national origin or ancestry, physical or mental disability, medical condition, sexual orientation, pregnancy, military or veteran status, citizenship status, and genetic information.

Illumina conducts background checks on applicants for whom a conditional offer of employment has been made. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable local, state, and federal laws. Background check results may potentially result in the withdrawal of a conditional offer of employment. The background check process and any decisions made as a result shall be made in accordance with all applicable local, state, and federal laws.

Illumina prohibits the use of generative artificial intelligence (AI) in the application and interview process. If you require accommodation to complete the application or interview process, please contact [e-mail].

To learn more, visit: https://www.dol.gov/ofccp/regs/compliance/posters/pdf/eeopost.pdf.

The position will be posted until a final candidate is selected or the requisition has a sufficient number of qualified applicants. This role is not eligible for visa sponsorship.

The potential of genomics to change the world is unparalleled. At Illumina, we are leading the way. Our technology empowers researchers and clinicians globally to improve cancer treatments, change the course of diseases, protect the environment, and fight food insecurity.

We are made up of dedicated professionals, all-in on creating a better world – and we need every skill set on our path to making genomics useful for all.

Learn more about life at Illumina.

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