Senior Scientist, EDDC

Agency for Science, Technology and Research; Singapore; On-site; SGD 80,000 - 120,000; Full time

Job summary

A leading research organization in Singapore seeks a Senior Scientist to join their Immunology and Inflammation discovery group. This role involves leading preclinical research, developing assays, and mentoring junior scientists. Ideal candidates should possess a Ph.D. in Immunology or a related field, with over 8 years of experience and a strong background in immune cell biology. This position offers the opportunity to engage in innovative therapeutic developments addressing unmet medical needs.

Qualifications

• Ph.D. in a related field with > 8 years working experience, minimally 3 years in the industry.
• Strong expertise in immune cell biology and autoimmune disease models.
• Experience with primary human PBMCs.

Responsibilities

• Lead preclinical research programs focused on validating therapeutic targets.
• Develop and optimize cell-based assays to support drug discovery.
• Mentor and train junior scientists.

Skills

Immunology

Molecular Biology

Translational Research

Cell-based Assays

Data Analysis

Education

Ph.D. in Immunology, Cell Biology, Molecular Biology

Tools

Flow Cytometry

Bioinformatics Tools

Job description

At Experimental Drug Development Centre (EDDC), we are dedicated to discovering and developing novel therapeutics through close collaboration with public sector institutions and industry partners. Drug discovery is a complex and resource-intensive journey, and we harness AI and data-driven strategies to improve the success rate of our programs. As part of our long-term strategy, we initiate projects where confidence in the therapeutic targets is strengthened by insights from patient-derived datasets. Like many biotech and pharmaceutical companies that are expanding into inflammation and immunology (I&I) disease areas, our approach reflects this growing trend and aims to deliver innovative solutions to address significant unmet medical needs in this area.

We are seeking a highly motivated and experienced Senior Scientist to join our I&I discovery group. The ideal candidate will have a strong background in immunology, molecular biology, and translational research. This is an exciting opportunity to be a part of the team working on the discovery of novel therapeutics and engaging in preclinical drug development from target exploration to drug candidate selection within the I&I therapeutic space.

Principle Roles & Responsibilities:

Lead and design preclinical research programs focused on identifying and validating novel therapeutic targets in immunology.

Develop and optimize cell-based assays, flow cytometry panels, and molecular biology techniques to support drug discovery.

Participate in the evaluation of internal as well as external collaborative projects.

Analyze, interpret, and present complex data to internal stakeholders and external partners.

Stay up to date with relevant scientific literature, research on translatability of preclinical disease models and novel mechanisms of action of particular importance within the I&I therapeutic space.

Collaborate with cross-functional teams including medicinal chemistry, antibody technology, in vivo pharmacology, computational biology and clinical development.

Mentor and train junior scientists, providing technical guidance, fostering scientific development, and supporting career growth within the team.

Requirements:

Ph.D. in Immunology, Cell Biology, Molecular Biology, or related fieldwith > 8 years working experience and minimally 3 years experience in the industry sector.

Strong expertise in immune cell biology, cytokine signalling, and autoimmune disease models.

Experience with primary human PBMCs, along with a strong understanding of tissue repair and regeneration in the context of immune resolution.

Proven expertise in developing and optimizing cell-based functional assays.

Excellent communication and presentation skills, with the ability to clearly convey scientific concepts and influence stakeholders across multidisciplinary teams.

Proven track record of scientific innovation, publications, and project leadership.


Ability to work independently and collaboratively in a fast-paced, dynamic environment.

Experience with biologics or small molecule therapeutics is preferred.

Familiarity with bioinformatics tools and multi-omics data analysis is preferred.