Senior NGS Laboratory Technician / NGS Laboratory Supervisor

GENECAST INNOTECH PTE. LTD.; Singapore; On-site; SGD 70,000 - 110,000; Full time

Job summary

GENECAST INNOTECH PTE. LTD. in Singapore seeks a Senior NGS Laboratory Technician / NGS Laboratory Supervisor to oversee complex molecular diagnostic testing and daily lab operations.

You will lead end-to-end NGS workflows, ensure quality and timeliness, mentor junior staff, and provide technical support to clients and cross-functional teams in a fast-paced clinical setting. Strong troubleshooting, documentation, and adherence to SOPs are essential, as is ability to train staff and drive

Qualifications

• Minimum 3–4 years of hands-on experience in NGS and molecular diagnostics, preferably in a clinical laboratory.
• Prior experience as a senior technician, team lead or laboratory supervisor is highly preferred.
• Strong technical knowledge of NGS workflows, library preparation, sequencing chemistry and sequencer operations.

Responsibilities

• Independently perform end-to-end NGS workflows, including nucleic acid extraction, library preparation and sequencing on Illumina and/or MGI platforms.
• Perform molecular diagnostic testing in accordance with SOPs and quality requirements.
• Ensure accurate and timely completion of testing to meet turnaround times.
• Assist Lab Operation Head with daily laboratory operations, inventory management, SOP updates and workflow optimisation.
• Maintain records for instrument maintenance, calibration and QC activities.
• Support management and maintenance of sequencers, liquid handlers and other equipment.
• Conduct root-cause analysis for assay anomalies, instrument issues and QC results.
• Support Quality Management System (QMS) implementation and maintenance.
• Identify opportunities for continuous process improvement.
• Provide NGS technical training and onboarding for new staff.
• Conduct competency assessments and ongoing coaching.
• Promote good laboratory practices and compliance with procedures.
• Provide technical support to clients and coordinate with internal teams to resolve issues.

Skills

NGS workflows

Library preparation

Sequencer operations

Troubleshooting

Documentation

Client liaison

Mentoring

English communication

Mandarin a plus

Education

Diploma in Medical Laboratory Technology

Bachelor’s in Biomedical Science/Medical Laboratory Science/Medical Laboratory Technology

Equivalent qualification acceptable

Job description

Job Title: Senior NGS Laboratory Technician / NGS Laboratory Supervisor
Work Location: Singapore

Job Purpose & Summary
We are seeking an experienced and qualified Senior NGS Laboratory Technician / NGS Laboratory Supervisor to support and oversee next-generation sequencing (NGS) laboratory operations. The successful candidate will be responsible for performing complex molecular diagnostic testing, supporting daily laboratory management, maintaining quality standards, and providing technical guidance and training to junior laboratory personnel.

The ideal candidate should possess strong technical expertise in NGS and molecular diagnostics, excellent troubleshooting and problem-solving skills, and the ability to work independently while ensuring compliance with applicable laboratory standards, quality requirements and established standard operating procedures (SOPs).

Key Responsibilities

1. Clinical Testing & Laboratory Operations

• Independently perform end-to-end NGS workflows, including nucleic acid extraction, library preparation and sequencing using Illumina and/or MGI platforms.
• Perform molecular diagnostic testing in accordance with established SOPs and quality requirements.
• Ensure accurate and timely completion of testing to meet required turnaround times.

2. Lab Management & Support

• Assist the Lab Operation Head with daily laboratory operations, inventory management, SOP updates and workflow optimisation.
• Maintain proper records for instrument maintenance, calibration and QC activities.
• Support the management and maintenance of sequencers, liquid handlers and other laboratory equipment.

3. Troubleshooting & Quality Assurance

• Conduct root-cause analysis and troubleshooting for assay anomalies, instrument issues and unsatisfactory QC results.
• Support the implementation and maintenance of the laboratory Quality Management System (QMS).
• Identify opportunities for continuous process improvement.

4. Training & Mentorship

• Provide NGS technical training and laboratory safety onboarding for new and junior laboratory staff.
• Conduct technical competency assessments and provide ongoing coaching and support.
• Promote good laboratory practices and compliance with established procedures.

5. Client and Onsite Technical Support

• Provide technical support and serve as a liaison for clients and key account sites when required.
• Coordinate with internal departments and cross-functional teams to resolve technical and operational issues.
• Support urgent laboratory operational requirements and work additional hours when necessary, subject to applicable employment requirements.

Qualifications & Requirements

Professional Qualifications – Must meet at least one of the following:

• Diploma in Medical Laboratory Technology; or
• Bachelor’s Degree in Biomedical Science, Medical Laboratory Science or Medical Laboratory Technology; or
• Equivalent qualification acceptable to the Director-General of Health.

Experience

• Minimum 3–4 years of hands-on experience in NGS and molecular diagnostics, preferably in a clinical laboratory environment.
• Prior experience as a senior technician, team lead or laboratory supervisor is highly preferred.

Key Competencies

• Strong technical knowledge of NGS workflows, library preparation, sequencing chemistry and sequencer operations.
• Good troubleshooting, root-cause analysis and independent problem-solving skills.
• Ability to work independently, manage competing priorities and perform effectively under pressure.
• Strong organisational skills and attention to detail.
• Good written and verbal communication skills in English.
• Ability to understand Mandarin will be an advantage.
• Strong interpersonal skills, with the ability to train and mentor junior staff and collaborate effectively with clients and cross-functional teams.