Senior Bioinformatics Computational Scientist

LIFE TECHNOLOGIES HOLDINGS PTE. LTD.; Singapore; On-site; SGD 60,000 - 80,000; Full time

Job summary

A leading biotechnology company in Singapore is seeking a Senior Bioinformatics Computational Scientist to apply AI and computational biology to enhance assay design for research and diagnostics. The ideal candidate should have a Master's degree or PhD, along with expertise in molecular biology and AI technologies. This role offers the opportunity to contribute to advancements in science and improve health outcomes globally.

Benefits

Collaborative interdisciplinary team

Supportive career development

Mission-driven organization

Qualifications

• 2+ years experience in a relevant field if holding an MS degree; PhD preferred.
• Deep expertise in molecular biology and genomic-based assay technologies.
• Hands-on experience with AI/ML models and large language models.

Responsibilities

• Automate and scale PCR-based assay design for real-time qPCR and digital PCR.
• Build end-to-end computational solutions that replace manual processes.
• Innovate bioinformatics tools and pipelines using machine learning frameworks.

Skills

Computational biology

AI/ML application

Workflow automation

Molecular biology knowledge

Education

MS or PhD in bioinformatics, computational biology, or related field

Tools

Bioinformatics tools

ML frameworks

Job description

About the Role

We are seeking a highly motivated Senior Bioinformatics Computational Scientist to transform how assays are designed and developed for oncology, infectious disease, and beyond. Your work will accelerate the discovery and development of assays that advance basic research, drug discovery, diagnostics, and plant/animal health globally. By merging computational biology, automation, modern data engineering, and artificial intelligence/machine learning, you will contribute to shaping the future of how biology is done.

In this role, you will

• Apply computational biology and AI/ML to automate and scale PCR-based assay design for real-time qPCR and digital PCR.
• Digitize and automate assay development by building end-to-end robust computational solutions and pipelines that replace manual processes with efficient, reproducible, and scalable workflows.
• Drive continuous innovation of bioinformatics tools and pipelines by applying large language models and machine learning frameworks to biological data, pioneering new ways.

Responsibilities

• Apply computational biology and AI/ML to automate and scale PCR-based assay design for real-time qPCR and digital PCR.
• Digitize and automate assay development by building end-to-end robust computational solutions and pipelines that replace manual processes with efficient, reproducible, and scalable workflows.
• Drive continuous innovation of bioinformatics tools and pipelines by applying large language models and machine learning frameworks to biological data, pioneering new ways.

Qualifications

• MS degree with 2+ years of experience or PhD in bioinformatics, computational biology, computer science, or related field.
• Deep expertise in molecular biology and genomic-based assay technologies.
• Proficiency in building computational pipelines and workflow automation.
• Hands-on experience in applying AI/ML models, including LLMs, to biological data.
• Proficiency in standard bioinformatics tools and modern ML frameworks
• Strong communicator who thrives both independently and as part of a global, interdisciplinary team.
• Passion for advancing the role of AI in biology to make a measurable impact on human health.

Preferred Qualifications

• Experience in cloud-based model deployment (AWS, GCP, or Azure).
• Background in infectious disease genomics (e.g., SARS-CoV-2, HIV, TB).
• Familiarity with wet-lab workflows and collaboration with assay development teams.
• Knowledge of assay readout analysis, performance evaluation, and statistical modeling of PCR data.

Why Join Us?

• Collaborate with an interdisciplinary team of scientists, engineers, and innovators across the globe.
• Contribute to a mission-driven organization where your work helps advance science and improve lives worldwide.
• Develop your career in a supportive, forward-looking environment that values both innovation and impact.

Thermo Fisher Scientific is an EEO/Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status.