Scientist/Senior, Biotherapeutics Development (BTI)

A*STAR - Agency for Science, Technology and Research; Singapore; On-site; SGD 60,000 - 90,000; Full time

Job summary

A leading research agency in Singapore seeks a motivated Scientist for its Biotherapeutics Development group. The candidate will focus on developing biotherapeutics aimed at clinical applications. Key responsibilities include characterising monoclonal antibodies, conducting in vivo studies, and collaborating with teams. A PhD in relevant fields is required, along with practical experience in molecular biology techniques. Strong communication and organisational skills are essential for this role.

Qualifications

• PhD degree in Biomedical Science, Cancer Science, Immunology, or a related field is required.
• Familiarity with selection criteria for lead and hit candidates.
• Interest in translational and applied research with industry collaboration.

Responsibilities

• Characterise and evaluate monoclonal antibodies and their targets.
• Contribute to therapeutics development through candidate identification.
• Conduct in vivo studies including immunisations and tumour models.
• Collaborate with project teams and manage mentorship.
• Prepare presentations, reports, and grant proposals.

Skills

Cellular and molecular biology

Strong organisational skills

Collaboration

Communication skills

Education

PhD degree in Biomedical Science, Cancer Science, Immunology, or relevant disciplines

Tools

Flow cytometry

Western blot

ELISA

Immunoprecipitation

Mammalian cell transfection

Job description

We are seeking a highly motivated Scientist to join our Biotherapeutics Development group. The successful candidate will contribute to research activities developing biotherapeutics with a goal towards clinical applications and commercialisation.

Key Responsibilities

• Characterise and evaluate monoclonal antibodies (mAbs), its antigen target and mechanism of action needed for a pre‑clinical dossier
• Contribute to therapeutics development pipeline through hit and lead identification
• Conduct in vivo studies, such as immunisations and tumour xenograft models
• Work in project teams with internal and external collaborators
• Contribute to mentorship of students and interns
• Prepare presentation slides, reports, technology disclosures, grant proposals
• Maintain accurate and timely experimental records
• Support routine lab operations, including procurement, equipment maintenance, lab safety compliance, and general housekeeping

Job Requirements

• A PhD degree in Biomedical Science, Cancer Science, Immunology, or relevant disciplines
• Familiar with the requirements needed for selection of potential lead and hit candidates
• A strong interest in the translational and applied aspects of research, including collaborations with industry partners.
• Practical experience in cellular and molecular biology (such as cell culture, flow cytometry, western blot, ELISA, immunoprecipitation, mammalian cell transfection, immunohistochemistry, bioassays, and data analysis) and in vivo studies
• Strong organisational and communication skills
• Able to work independently and collaboratively in a team