Scientist, Laboratory of Cancer Epigenetic Regulation (GIS)

The Laboratory of Cancer Epigenetic Regulation, helmed by GIS Chief Scientific Officer Patrick Tan, is seeking a Bioinformatics Research Fellow to join a multi-institutional effort that employs deep multi-omics phenotyping to uncover cancer biomarkers that correlate with clinical outcomes including therapeutic response, resistance, and recurrence. Led by an award-winning thought leader in the field of Asian gastrointestinal cancer research with over 300 peer-reviewed publications in leading journals such as Cell, Cancer Discovery, Nature Genetics, and Science, the Laboratory of Cancer Epigenetic Regulation applies integrative (epi)genomic approaches to address biological and translational questions in cancer, to devise rational diagnostic/therapeutic strategies for cancer patients. The candidate will develop and/or apply diverse bioinformatic tools and pipelines for integrative multi-omics bioinformatics analyses (whole-genome sequencing (WGS), RNA-seq, ChIP-seq, metabolomics) to study evolutionary trajectories between primary and recurrent samples.

Responsibilities:

1. Analyze, integrate and interpret multi-omics data such as whole-genome sequencing (WGS), RNA-seq, ChIP-seq and metabolomics.
2. Lead manuscript writing for high impact journal publication.
3. Deliver scientific presentations.
4. Collaborate with clinicians and scientists from local and international institutions.
5. Assist the PI in grant applications.

Skills/Background:

1. PhD in a Biology/Computational Biology related field.
2. Candidates with and without postdoctoral experience will be considered.
3. Experience with analyzing NGS data (e.g., WES, WGS, ChIP-Seq, ATAC-Seq, RNA-seq, single-cell data etc).
4. Highly motivated, able to work independently and committed team player.
5. A track record of peer-reviewed publications in relevant areas to be provided.