Research Officer (HWP Lab), IMCB

A*STAR - Agency for Science, Technology and Research; Singapore; On-site; SGD 40,000 - 60,000; Full time

Job summary

A*STAR - Agency for Science, Technology and Research is seeking a highly motivated Research Officer to join our team in Singapore. The successful candidate will engage in projects related to liver cancer and cancer metabolism, undertaking in vitro experiments and managing animal studies.

The ideal applicant will hold a Bachelor’s or Master’s degree in Biological Science, possess hands-on lab experience, and have strong communication skills. Excellent opportunities to grow within a collaborative environment are offered.

Qualifications

• 6-12 months of relevant lab and animal work experience.
• Hands-on experience with basic rodent handling and molecular assays.
• Excellent communication skills and rigorous data integrity.

Responsibilities

• Conduct in vitro & wet lab experiments including assays.
• Manage routine animal husbandry and experiments.
• Maintain accurate monitoring and reporting of experimental data.

Skills

Cell culture

Molecular biology

Animal handling

Scientific communication

Education

Bachelor's or master's in Biological Science

Tools

PCR/qPCR

Western blot

Job description

We are looking for a qualified individual who is highly motivated, detail-oriented, passionate and committed to laboratory ethics, to be employed for the role of Research Officer. The successful candidate will work with a dynamic team on projects relating to liver cancer, cancer metabolism, cancer immunology and non‑alcoholic steatohepatitis‑associated hepatocellular carcinoma (NASH‑HCC) progression. This role offers excellent opportunities to work within a multidisciplinary team and manage end‑to‑end experimental data packages.

Key Responsibilities

• In vitro & wet lab experiments: Cell culture, molecular biology and assays (e.g. RNA/protein extraction, RT‑qPCR, Western blotting and ELISAs), microscopy etc
• Routine animal husbandry and colony management: Breeding, weaning, ear‑notching/tagging, genotyping and tracking of animal cohorts.
• In vivo handling and experiments: Diet/treatment dosing regimes, body weight & composition analyses, blood sampling and terminal blood collection, tissue collection and sample preparation, perfusion, tissue/organ imaging, serum measurements etc
• Data & Lab Management: Maintain accurate monitoring and reporting of experimental set‑up, protocols, results and research findings, support general lab operations, buffer preparation and reagent stock-taking
• Scientific Communication: Communicate regularly with supervisor and PI and attend lab meetings with PI and rest of the lab to discuss scientific progress and direction

Qualifications & Requirements

• Bachelor’s or master’s qualifications in Biological Science and Life Science disciplines or equivalent field
• At least 6‑12 months of relevant experience in laboratory and animal work (prior academic internships, Final Year Projects, or industry attachment counts)
• Hands‑on experience with basic rodent handling and restraint, competence in basic molecular biology and cellular assays (cell culture, PCR/qPCR, Western blot)
• Bonus/Advantageous: Prior completion of certified animal care and use courses (e.g., RCULA certification), technical competency in end‑point sampling and tissue collection
• Excellent interpersonal, written and oral communication skills with a rigorous approach to experimental controls, reproducibility, and data integrity
• Excellent collaborative mindset with ability to multitask across multiple project streams and work both in teams and independently
• Highly motivated and willing to learn