Research Fellow (Pharmacy and Pharmaceutical Sciences)

National University of Singapore; Singapore; On-site; SGD 70,000 - 100,000; Full time

Job summary

National University of Singapore invites applications for a Research Fellow in Pharmacy and Pharmaceutical Sciences. The successful candidate will work in Dr.

Alexander Vinogradov's laboratory on late-stage peptide modification strategies and mRNA display-based discovery of cyclic peptides targeting therapeutically relevant proteins. Responsibilities include designing and conducting experiments, data analysis, preparing publications and presentations, giving group updates, and helping maintain

Qualifications

• PhD in organic chemistry, peptide chemistry, combinatorial chemistry, chemical biology, bioorganic chemistry, or biological chemistry.
• 3–5 years’ experience in primary research preferred; PhD graduates without experience are welcome to apply.

Responsibilities

• Design and conduct experiments in bio-organic chemistry, chemical biology, and biochemistry.
• Analyze experimental data.
• Prepare research findings for publication in peer-reviewed journals and presentation at international conferences.
• Present oral research updates in group meetings and prepare periodic written updates.
• Contribute to maintenance of laboratory equipment.

Skills

Synthetic Organic Chemistry

Air-free techniques

Peptide chemistry

Solid-phase Synthesis

Analytical chemistry

mRNA display

LC/MS

HPLC

NMR

UV-Vis

Communication skills

Team collaboration

Education

PhD in Organic/Peptide/Combinatorial/Chemical/Bioorganic/Biological Chemistry

Tools

LC/MS

HPLC

NMR

Job description

Job Title: Research Fellow (Pharmacy and Pharmaceutical Sciences)

University-Level Unit: Science

Faculty/Department-Level Unit: Pharmacy and Pharmaceutical Sciences

Employee Category: Research Staff

Location_ONB: Kent Ridge Campus

Posting Start Date: 09/10/2026

Job Description

The successful candidate will work in the laboratory of Dr. Alexander Vinogradov (NUS Presidential Young Professor; lab website: https://vinogradov.science) on developing late-stage peptide modification strategies and utilizing them for drug discovery applications. Broadly, the project is dedicated to developing an mRNA display-compatible peptide cyclization and modification strategies. These strategies will be utilized for mRNA display-based discovery of cyclic peptides targeting proteins with high therapeutic potential.

The Candidate Will Be Responsible For

• Design and conduct experiments in bio-organic chemistry, chemical biology, and biochemistry.
• Analyze experimental data.
• Prepare research findings for publication in peer-reviewed journals and presentation at international conferences.
• Present oral research updates in group meetings and prepare periodic written updates.
• Contribute to maintenance of laboratory equipment.

Qualifications

• PhD degree in one of the following areas: organic chemistry, peptide chemistry, combinatorial chemistry, chemical biology, bioorganic chemistry, or biological chemistry.

Skills

• Expertise in synthetic organic chemistry, including air-free techniques, syntheses in water, late-stage modification of complex compounds, peptide chemistry, including solid-phase peptide synthesis, analytical characterization, and peptide modification.
• Strong knowledge of fundamental organic and peptide chemistry.
• Understanding of combinatorial chemistry concepts and expertise in mRNA display or other genetically encoded combinatorial methods (yeast display, phage display, DELs) are not required but will be considered an asset.
• Expertise in analytical and biophysical techniques of peptides and small molecules (LC/MS, HPLC, UV-Vis spectroscopy, NMR).
• Excellent written and verbal communication skills.
• Ability to work both independently and collaboratively within a team.

Experience

• Candidates with at least 3-5 years’ experience in primary research.
• PhD graduates without experience are welcome to apply.

Req ID: 34631