Research Associate (Biological Interfaces)

Nanyang Technological University Singapore; Singapore; On-site; SGD 45,000 - 75,000; Full time

Job summary

NTU Singapore’s Institute for Digital Molecular Analytics & Science (IDMxS) invites applications for a Research Associate to advance lipid nanoparticle (LNP) carrier work for mRNA delivery. You will collaborate with senior researchers to study physical properties, interactions with host cells, and contribute to both fundamental understanding and translational outcomes.

You will perform a range of biophysical and biochemical experiments, document findings, and help prepare publications while

Qualifications

• Master’s degree in life sciences (biochemistry, molecular cell biology, or related disciplines).
• Experience with soft matter structural characterization techniques.
• Familiar with lab operations, safety and management matters.
• Strong written and oral communication; ability to write reports and review publications.
• Experience with fluorescence microscopy, spectroscopy, cell cultures and biochemical assays.

Responsibilities

• Use structural characterization techniques to understand LNP-mRNA aggregates with improved transfection efficiency and protein expression.
• Perform biophysical/biochemistry/molecular biology experiments and analyze data.
• Maintain effective communication among group members.
• Accurately document laboratory work and ensure traceability.
• Draft scientific publications and present findings internally and externally.
• Comply with laboratory safety standards and guidelines.
• Assist in lab management tasks as needed.
• Mentor junior team members.

Skills

Biochemistry

Molecular biology

Soft matter characterization

Scientific writing

Team communication

Education

Master's degree in life sciences

Tools

Fluorescence microscopy

Spectroscopy

Cell culture

Molecular biology techniques

Biochemical assays

Job description

The Institute For Digital Molecular Analytics & Science (IDMxS) is a unique interdisciplinary Research Centre of Excellence (RCE), funded by National Research Foundation, Ministry of Education (Singapore), Nanyang Technological University and National University of Singapore. Hosted by NTU, IDMxS is focused on development of core science to drive a paradigm shift in molecular detection and analysis to link the biomolecular world of life with the networked world of technology.

IDMxS is looking for motivated individual to join us as Research Associate to advance research in the development of lipid nanoparticle (LNP) based carriers for the delivery of mRNA related biomolecular cargo. The role will focus on working with senior researchers and collaborators for studying the physical properties of custom-formulated LNPs containing synthetic dopants such as conjugated molecules and their interactions with host cells. The position will contribute to both fundamental understanding and translational outcomes, supporting the Institute’s mission to integrate life sciences with physical, chemical, and materials sciences and engineering for novel molecular analytics.

Key Responsibilities:

• Use a range of structural characterization techniques to understand the physical features of LNP-mRNA aggregates that exhibit improved transfection efficiency and protein expression.
• Execute biophysical/biochemistry/molecular biology experiments and perform data analysis.
• Ensure effective communications among group members.
• Ensure accurate and systematic documentation of laboratory work.
• Draft scientific publications, present research findings internally and externally.
• Comply with all laboratory safety standards and guidelines.
• Assist in lab management matters when necessary.
• Guide junior members of the team.

Requirements:

• Master’s in life science, biochemistry, molecular cell biology, or other related disciplines.
• Experience in soft matter structural characterization techniques.
• Familiar with lab operation, lab safety and management matters.
• Strong communication skills and ability to write research reports, publish and critically review publications.
• Experience with most of the following analytical technologies, including fluorescence microscopy, spectroscopy, cell cultures, molecular biology techniques, biochemical assays, etc.

We regret to inform that only shortlisted candidates will be notified.

Hiring Institution: NTU