Animal Model Handling:
Conduct routine handling and care of laboratory mice, ensuring adherence to ethical and welfare standards.
Support experimental setups in mouse models to study disease pathogenesis, progression, and therapeutic responses in haematologic malignancies.
Perform injections, tissue sampling, and necropsies as required for experiments.
Data Collection and Analysis:
Assist in collecting and processing biological samples (e.g., blood, tissue) from mouse models for downstream molecular analyses.
Maintain accurate records of experiments, data collection, and sample inventory in a clinical database for integrated bioinformatics analysis.
Genomic and Proteomic Support:
Assist in sample preparation for genomics and proteomics studies, including DNA/RNA extraction and preparation for sequencing and protein assays.
Support preclinical validation of molecular markers and therapeutic targets identified from genomic studies.
Laboratory Support and Maintenance:
Ensure lab equipment related to mouse work is well-maintained and calibrated.
Follow all safety protocols and maintain a clean, organized work environment.
Assist in the maintenance of a comprehensive tissue bank, ensuring high-quality source material is available for research.
Collaboration and Reporting:
Collaborate closely with senior researchers, assisting in the analysis of data from mouse models.
Report findings and observations to the research team and contribute to discussions on the impact of preclinical findings on clinical applications.