Project Engineer – Cleanroom Construction (Engineering Services)

ESCO ASTER PTE. LTD.; Singapore; On-site; SGD 70,000 - 90,000; Full time

Job summary

A leading company in life sciences seeks a Project Engineer to oversee turnkey cleanroom projects within the pharmaceutical and healthcare sectors. The candidate will be responsible for project initiation, design coordination, procurement, and construction management while ensuring compliance with industry standards. This position offers an opportunity to make a significant impact in a rapidly evolving field and work alongside multidisciplinary teams.

Qualifications

• At least 5 years' relevant experience in the pharmaceutical or relevant industry.
• Strong knowledge and hands-on experience in cleanroom construction.
• Excellent oral and written communication skills.

Responsibilities

• Translate client URS into project scope, schedule, and cost baseline.
• Lead design coordination and ensure regulatory compliance.
• Manage construction and commissioning of cleanroom projects.

Skills

Communication

Project Management

Risk Management

Stakeholder Management

Education

Degree/Diploma in Mechanical, Marine or Industrial Engineering

Tools

Primavera

MS Project

Job description

The Opportunity

Esco Lifesciences Group is Singapore’s most globalized life sciences company, with annual revenues close to SGD 200M and global operations in over 42 locations and 26 direct countries across North America, Europe, Asia, Oceania.

Esco Aster Pte Ltd is an affiliate of Esco Lifesciences Group and was first incorporated in 2017.

Esco Aster is a contract research development and manufacturing organization founded and deeply rooted by scientists enabling fellow scientists to translate their bench work into commercially available products at affordable prices.

Our scientific work is in emerging and frontier biology utilizing cells as a final product or deriving products from cells which often we use cells as the factory to derive our target product.

Our first commercial breakthrough success is Esco Aster is commercially first in class being first in the world to be certified for cultivated/cell-based meat to FSSC 22000 and by a competent food regulatory body.

We are first in the region to operate an end-to-end integrated full cell line creation/immortalization or engineered cell line, cell culture process development, analytical development for stem cells and exosomes with full cGMP Capabilities from Drug Substance and small-scale fill & finish for final Cell Therapy Product.

The work we do creates a remarkable and lasting impact on our world. We offer you an opportunity to be part of this exciting journey to own your career and firsthand exposure to new emerging modalities supporting translational sciences.

Join us as we redefine BioSolutions for One World and One Health for the current and future generations to come.

Esco Aster.

One World Biosolutions for One Health.

The Scope

You will be part of Esco Aster’s Engineering team and contribute to the overall site mission and objectives. As a Project Engineer you will be a key support function in the end-to-end delivery of turnkey cleanroom projects—encompassing design coordination, construction, commissioning, and qualification—for clients in the pharmaceutical, semiconductor, healthcare, and research-laboratory sectors. Drawing on a strong engineering foundation (mechanical, electrical, or related), you will ensure each project is executed safely, on time, within budget, and in full compliance with ISO 14644, cGMP, and relevant local building codes. You will be the single point of accountability, steering multidisciplinary teams (HVAC, architectural, MEP, process utilities, controls, validation) and managing stakeholders ranging from client user groups to trade contractors and regulatory inspectors.

Primary work location: Ayer Rajah Crescent, Singapore (Office), and customer sites

Reporting to: Head of Engineering

Job Responsibilities

Project Initiation & Planning

• Translate client URS into a definitive project scope, WBS, schedule (Primavera / MS Project), and cost baseline.
• Lead constructability and design-for-cleanliness reviews (ISO class, airflow, pressurization, material & personnel flows).
• Develop risk register and mitigation plans; obtain all permits and EHS approvals.

Design Coordination

• Interface with internal designers and external A/E partners to align layouts, HVAC zoning, filtration, finishes, and utility requirements.
• Verify design meets regulatory requirements (FDA, EMA, PIC/S, USP <797>/<800>, ISO 14644-1/2/3/4/5).

Procurement & Contracting

• Prepare bid packages, evaluate vendors for modular panels, FFUs, HEPA filters, process piping, and BMS/EMS systems.
• Negotiate purchase orders and sub-contracts; track long-lead items to protect critical path.

Construction Management

• Run daily/weekly site coordination meetings; enforce safety (LOTO, hot-work, clean-build protocols).
• Manage field supervision, QA/QC inspections, punch lists, and change-order control.
• Monitor schedule, productivity, earned-value, and cash flow; issue progress reports to internal leadership and clients.

Commissioning & Qualification

• Oversee IQ/OQ execution: airflow visualization, particle counts, differential-pressure mapping, temperature/humidity stratification, and recovery tests.
• Coordinate with validation teams to close deviations and compile turnover package (DQ/IQ/OQ reports, as-built drawings, SOPs).

Project Close-out & Handover

• Secure client sign-off and occupancy certificates; organize training for operations staff.
• Perform lessons-learned meetings and archive project documentation for ISO / cGMP audits.

· Undertake tasks assigned by leaders as and when appropriate.

Requirements

· Degree/Diploma in Mechanical, Marine or Industrial Engineering with at least 5 years' relevant experience in the pharmaceutical or relevant industry.

· Strong knowledge and hands on experience in execution of cleanroom construction projects, either as owner or as contractor.

· Preferably 5–10 years managing clean-build or high-spec environments (ISO 5–8, Class 100–100 000) in pharma, fab, or healthcare

· Solid grasp of airflow design, contamination-control, MEP coordination, BMS/EMS systems, and ISO/cGMP standards.· Expert knowledge of HVAC, central plant utility systems, Building management systems (BMS), Environment monitoring system (EMS) and clean room technology.

· Familiar and understand GxP requirement for routine utilities and facility operation.

· Preferable experience with start-up, commissioning and qualification of utilities equipment, including requirements for documentation and testing.

· Able to work independently, self-starter, self-motivated and task oriented.

· Excellent oral and written communication skills with high computer literacy.

· Customer service orientated mindset and able to develop strong working relationships with internal customers.

· Able to plan and ensure uninterruptable utility supplies to the end user for operational facilities A&A or upgrade

· Familiar with industrial/engineering/regulatory best practices, codes and standards.

· Willing to perform multiple and cross-functional tasks.

Interested candidates, please submit a Cover Letter and CV to [e-mail].