Process Science Engineer II (Lab)

SGP - 9928 Takeda Manuf SG Pte Ltd; Singapore; On-site; SGD 70,000 - 120,000; Full time

Job summary

Takeda in Singapore (Woodlands) seeks a highly capable professional to plan and execute laboratory experiments for small-scale process development and validation. You will support analytical activities and collaborate with cross-functional teams to ensure testing readiness for experiments.

The role covers cell culture, purification, media preparation, and documentation creation and review. Experience with cGMP and manufacturing/ development lab environments is required.

Qualifications

• Bachelor’s Degree in Biochemistry, Chemistry, Chemical Engineering, Biotechnology, or Biochemical Engineering with minimum 4 years of relevant experience or Master’s Degree with 2 years of relevant experience.
• Hands-on experience with cell culture/ upstream processes and/or downstream purification processes in a manufacturing or development / small scale lab environment.
• Has awareness of cGMP knowledge.

Responsibilities

• Plan and execute laboratory experiments according to internal and external guidelines for small scale process development and validation, process investigations and improvements, qualified scale down models and material use tests.
• Support analytical activities relevant to laboratory scale experiments. Work with the relevant cross functional or global teams to ensure that the testing support are in place for experiments.
• Design, plan and execute the laboratory experiments according to experimental plan timelines. Plan and execute activities required for laboratory experiments for eg, and not limited to cell culture/ purification/media/buffer preparation
• Create and review of laboratory documentation including procedures, forms, protocols and reports for routine activities and / or experiments according to relevant quality standards
• Analyse and summarize laboratory results. Compile results into laboratory reports. Support equipment troubleshooting in event of failures.
• Perform laboratory equipment maintenance and calibration as per laboratory procedures
• Plan and implement qualified scale down models through executing the experimental runs and drafting required documentation.
• Lead or support troubleshooting for any issues or atypical results from small scale studies
• Support the implementation of new technologies for small scale model development and improvement
• Lead implementation of new equipment in the laboratory.
• Lead 5S/6S activities within the laboratory and execute housekeeping activities within the lab
• Order and stock materials, including consumables and raw materials
• Support EHS audit walkdowns, and close audit CAPAs on time
• Responsibility to adhere to any applicable EHS requirements.
• Commitment to a fair and respectful relationship to others and behavior in accordance with Takeda’s Code of Conduct.

Skills

Laboratory operations

Cell culture

Purification processes

Analytical testing

Data recording

Cross-functional collaboration

Communication skills

Independent working

Flexible after-hours

Education

Bachelor’s degree in Biochemistry/Chemistry/Chemical Engineering/Biotechnology/Biochemical Engineering

Tools

Laboratory equipment

Cell culture systems

Job description

Primary Objectives of this Job

• Perform laboratory experiments, use tests or small-scale investigations
• Support or lead small-scale studies and data gathering for manufacturing operations (process investigations, improvement projects)
• Support or lead the evaluation of process improvements and design of small-scale experiments to implement process improvements
• Provide technical support in small scale experiment troubleshooting

Responsibilities

• Plan and execute laboratory experiments according to internal and external guidelines for small scale process development and validation, process investigations and improvements, qualified scale down models and material use tests
• Support analytical activities relevant to laboratory scale experiments. Work with the relevant cross functional or global teams to ensure that the testing support are in place for experiments.
• Design, plan and execute the laboratory experiments according to experimental plan timelines. Plan and execute activities required for laboratory experiments for eg, and not limited to cell culture/ purification/media/buffer preparation
• Create and review of laboratory documentation including procedures, forms, protocols and reports for routine activities and / or experiments according to relevant quality standards
• Analyse and summarize laboratory results. Compile results into laboratory reports. Support equipment troubleshooting in event of failures.
• Perform laboratory equipment maintenance and calibration as per laboratory procedures
• Plan and implement qualified scale down models through executing the experimental runs and drafting required documentation.
• Lead or support troubleshooting for any issues or atypical results from small scale studies
• Support the implementation of new technologies for small scale model development and improvement
• Lead implementation of new equipment in the laboratory.
• Lead 5S/6S activities within the laboratory and execute housekeeping activities within the lab
• Order and stock materials, including consumables and raw materials
• Support EHS audit walkdowns, and close audit CAPAs on time
• Responsibility to adhere to any applicable EHS requirements.
• Commitment to a fair and respectful relationship to others and behavior in accordance with Takeda’s Code of Conduct.
• Any other duties as assigned by supervisor.

Education and Experience Requirements

• Bachelor’s Degree in Biochemistry, Chemistry, Chemical Engineering, Biotechnology, Biochemical Engineering with minimum 4 years of relevant experience or Master’s Degree with 2 years of relevant experience.
• Hands-on experience with cell culture/ upstream processes and/or downstream purification processes in a manufacturing or development / small scale lab environment.
• Has awareness of cGMP knowledge

Key Skills and Competencies

• Strong experience in laboratory operations for biological upstream or downstream processes.
• Strong knowledge in analytical and cell culture/purification laboratory equipment
• Good communication skills
• Good stakeholder management and conflict management skills.
• Willingness to learn
• Team worker/ able to work in matrix environment
• Independent worker/ Self starter
• Flexible to be able to work after office hours where required to support laboratory experiments

Locations

SGP - Singapore - Woodlands

Worker Type Employee Worker Sub-Type Regular Time Type Full time

About Takeda

Takeda is an industry-leading, global pharmaceutical company with an unwavering dedication to putting patients at the center of everything we do. We live our values of Takeda-ism – Integrity, Fairness, Honesty, and Perseverance – and are united by our mission to strive towards Better Health and a Brighter Future for people worldwide through leading innovation in medicine. Here, everyone matters and you will be a vital contributor to our inspiring, bold mission. At Takeda, you will make an impact on people’s lives – including your own.

Takeda is an equal opportunity employer.