Operations Engineer -

Advanced Manufacturing Tech Solutions PTE. LTD. (AMTSOL); Singapore; On-site; SGD 60,000 - 120,000; Full time

Job summary

AMTSOL, a leader in life science manufacturing technology, seeks an Operations Engineer to support media and buffer operations on the shop floor. You will work with MES, SAP and distributed control systems to deliver compliant, well-documented production processes, spanning commissioning, water-run, engineering-run phases and material preparation in a GMP environment.

You will develop MES work instructions, maintain electronic batch records, review process instructions, and contribute to

Qualifications

• Five years' GMP manufacturing or operations experience.
• Hands-on experience setting up and running media and buffer operations.
• Experience with MES projects and SAP master data for buffers/media.
• Knowledge of GMP data integrity and electronic systems.

Responsibilities

• Set up and support media and buffer operations on the shop floor.
• Develop and maintain MES work instructions and electronic batch records for buffer and media.
• Review and test MES process instructions to ensure accuracy and compliance.
• Create and maintain SAP master data for buffer and media.
• Perform gap assessments and support implementation of controls.
• Author and update process SOPs and related documentation.
• Author, review and approve validation protocols and reports, and lead execution activities.
• Support commissioning, water-run and engineering-run phases, and project tasks related to material preparation.

Skills

Problem solving

Communication skills

GMP knowledge

Cross-functional collaboration

Education

Engineering, Life Sciences or related discipline degree

Tools

MES

SAP

DeltaV

Job description

AMTSOL:

A Leader in Life science Manufacturing Technology solutions, we are looking for top talent to be part of the dynamic team and drive the growth of the business.

Role Overview:

The Operations Engineer supports the set-up and running of media and buffer operations on the manufacturing shop floor, working across MES, SAP and distributed control-system platforms to deliver compliant, well-documented production processes. The role spans day-to-day operational support and project delivery activities — including commissioning, water-run and engineering-run phases and material preparation — within a GMP-regulated environment.

Key Responsibilities

• Set up and support media and buffer operations on the shop floor.


• Develop and maintain MES work instructions and electronic batch records for buffer and media.


• Review and test MES process instructions to ensure accuracy and compliance.


• Create and maintain SAP master data for buffer and media.


• Perform gap assessments and support implementation of controls.


• Author and update process SOPs and related documentation.


• Author, review and approve validation protocols and reports, and lead execution activities.


• Support commissioning, water-run and engineering-run phases, and project tasks related to material preparation

Requirements

• Degree in Engineering, Life Sciences or a related discipline (or equivalent experience).


• Minimum 5 years’ relevant experience in GMP manufacturing or operations.


• Hands‑on experience setting up and running media and buffer operations.


• Practical MES experience, ideally including new MES project delivery.


• Experience with DeltaV or similar distributed control systems.


• Experience in new product transfer / introduction to manufacturing systems and shop‑floor operations.


• Working knowledge of SAP master data for buffer and media.


• Good understanding of GMP and data integrity for electronic systems.


• Strong problem-solving and communication skills.