GMP Manufacturing Operations Engineer: Media, MES & Protocols

Advanced Manufacturing Tech Solutions (AMTSOL); Singapore; On-site; SGD 60,000 - 110,000; Full time

Job summary

AMTSOL, a leader in life science manufacturing technology solutions, is seeking an Operations Engineer to support the set‑up and running of media and buffer operations on the shop floor, interfacing with MES, SAP and DCS to deliver compliant, well‑documented production processes within a GMP framework.

The role spans day‑to‑day operational support and project delivery activities — including commissioning, water‑run and engineering‑run phases and material preparation — and requires hands‑on MES

Qualifications

• Degree in Engineering, Life Sciences or a related discipline.
• Minimum 5 years’ relevant GMP manufacturing or operations experience.
• Hands‑on experience setting up and running media and buffer operations.
• Practical MES experience, ideally including new MES project delivery.
• Experience with DeltaV or similar distributed control systems.
• Experience in new product transfer / introduction to manufacturing systems and shop‑floor operations.
• Working knowledge of SAP master data for buffer and media.
• Good understanding of GMP and data integrity for electronic systems.
• Strong problem-solving and communication skills.

Responsibilities

• Set up and support media and buffer operations on the shop floor.
• Develop and maintain MES work instructions and electronic batch records for buffer and media.
• Review and test MES process instructions to ensure accuracy and compliance.
• Create and maintain SAP master data for buffer and media.
• Perform gap assessments and support implementation of controls.
• Author and update process SOPs and related documentation.
• Author, review and approve validation protocols and reports, and lead execution activities.
• Support commissioning, water-run and engineering-run phases, and project tasks related to material preparation

Skills

GMP operations

MES project delivery

Data integrity

Problem solving

Communication

New product transfer

Education

Degree in Engineering, Life Sciences or related

Tools

SAP

DeltaV

Job description

AMTSOL, a leader in life science manufacturing technology solutions, is seeking an Operations Engineer to support the set‑up and running of media and buffer operations on the shop floor, interfacing with MES, SAP and DCS to deliver compliant, well‑documented production processes within a GMP framework.

The role spans day‑to‑day operational support and project delivery activities — including commissioning, water‑run and engineering‑run phases and material preparation — and requires hands‑on MES