NGS Laboratory Technologist

GENECAST INNOTECH PTE. LTD.; Singapore; On-site; SGD 50,000 - 73,000; Full time

Job summary

Genecast is seeking a motivated and detail-oriented NGS Laboratory Technologist to support daily lab operations and molecular diagnostic testing, gaining practical experience in NGS, molecular diagnostics, and precision oncology within a quality-focused environment.

You will perform routine procedures including DNA/RNA extraction, PCR, library preparation, sequencing, and data QC; process clinical specimens; operate sequencers and automated systems; and maintain equipment and records in

Qualifications

• Molecular biology techniques including DNA/RNA extraction, PCR, and NGS library prep.
• Experience with clinical sample processing and molecular diagnostics workflows.
• Familiarity with NGS platforms such as MGI or Illumina sequencing systems.
• Knowledge of laboratory QC, SOPs, biosafety, and equipment operation.
• Ability to communicate in English; Mandarin is an advantage.

Responsibilities

• Perform routine laboratory procedures including DNA/RNA extraction, PCR, NGS library preparation, and sequencing to support molecular diagnostic workflows
• Receive, process, and prepare clinical specimens such as tissue, blood, and plasma samples for testing
• Operate and maintain NGS sequencers and automated liquid-handling systems to ensure reliable sequencing runs
• Conduct quality control checks on samples and sequencing data, documenting results accurately and timely
• Troubleshoot technical and equipment issues to minimize workflow disruptions
• Maintain laboratory equipment, reagents, and consumables following established procedures to ensure operational readiness
• Follow laboratory safety, biosafety, quality control, and contamination-prevention protocols to maintain a safe and compliant environment
• Keep the laboratory clean, organized, and compliant with regulatory standards
• Support laboratory projects, validation activities, and process improvements as assigned
• Collaborate effectively with team members and work independently on routine laboratory tasks

Skills

DNA/RNA extraction

PCR

NGS library preparation

NGS platforms

Clinical sample processing

Molecular diagnostics workflows

QC and data handling

English communication

Mandarin language advantage

Tools

Illumina sequencing systems

MGI sequencing platforms

Job description

Company Overview

Genecast is a precision oncology company advancing personalized cancer care through molecular diagnostics, translational research, and innovation. It supports cancer detection, genomic profiling, therapy selection, and disease monitoring using NGS, liquid biopsy, and multi-omics technologies.

Job Summary

We are seeking a motivated and detail-oriented NGS Laboratory Technologist to support daily lab operations and molecular diagnostic testing, gaining practical experience in NGS, molecular diagnostics, and precision oncology within a quality-focused environment.

Responsibilities

• Perform routine laboratory procedures including DNA/RNA extraction, PCR, NGS library preparation, and sequencing to support molecular diagnostic workflows
• Receive, process, and prepare clinical specimens such as tissue, blood, and plasma samples for testing
• Operate and maintain NGS sequencers and automated liquid-handling systems to ensure reliable sequencing runs
• Conduct quality control checks on samples and sequencing data, documenting results accurately and timely
• Troubleshoot technical and equipment issues to minimize workflow disruptions
• Maintain laboratory equipment, reagents, and consumables following established procedures to ensure operational readiness
• Follow laboratory safety, biosafety, quality control, and contamination-prevention protocols to maintain a safe and compliant environment
• Keep the laboratory clean, organized, and compliant with regulatory standards
• Support laboratory projects, validation activities, and process improvements as assigned
• Collaborate effectively with team members and work independently on routine laboratory tasks

Preferred competencies and qualifications

• Molecular biology techniques including DNA/RNA extraction, PCR, and NGS library preparation
• Experience with clinical sample processing and molecular diagnostics workflows
• Familiarity with NGS platforms such as MGI or Illumina sequencing systems
• Knowledge of laboratory quality control, SOPs, biosafety, and equipment operation
• Ability to communicate effectively in English; understanding Mandarin is an advantage