National University of Singapore

BRIC; Singapore; Hybrid; SGD 60,000 - 100,000; Full time

Job summary

BRIC in Singapore invites a Research Fellow to develop biomaterials for reprogramming tumor-associated cells in vivo, aiming to boost cancer immunotherapy. The project integrates material science, immunology and translational biology to create novel cancer therapies.

The candidate will design and characterise biomaterials, perform in vivo studies, and collaborate with multidisciplinary teams to advance immunotherapy approaches.

Qualifications

• PhD in material sciences, biomedical engineering and immunology.
• Experience in organic synthesis, immune characterisation and/or animal work.

Responsibilities

• Develop biomaterials for reprogramming tumor‑associated cells in vivo.
• Collaborate with multidisciplinary teams to advance immunotherapy.
• Characterise immune responses to biomaterials in preclinical models.

Skills

Organic synthesis

Immune characterisation

Animal work

Education

PhD in material sciences, biomedical engineering and immunology

Job description

A solid tumor contains a variety of cells, some of which are immuno-suppressed and metabolically inhibited while some are recruited by cancer cells as accomplices to support tumor development. Cell reprogramming is a powerful way using proteins and nucleic acids to steer the fates of cells into anti-cancer phenotypes. However, getting the reprogramming therapeutics into cells in vivo remains challenging. In this project, the research fellow will be developing biomaterials for reprogram tumor-associated cells in vivo, with the aim to boost cancer immunotherapy.

Requirements

PhD in material sciences, biomedical engineering and immunology. The candidate should have experience in organic synthesis, immune characterisation and/or animal work.