Medical Laboratory Scientist (Variant Scientist), DNA Diagnostics & Research Lab

KK WOMEN'S AND CHILDREN'S HOSPITAL PTE. LTD.; Singapore; On-site; SGD 60,000 - 80,000; Full time

Job summary

A prominent healthcare institution in Singapore is seeking an experienced Variant Scientist to analyze genetic variations and prepare reports. The role involves maintaining databases, collaborating with multidisciplinary teams, and contributing to scientific publications. Candidates should hold a Master's degree in life sciences and have at least 3 years of relevant experience.

Qualifications

• Minimum of 3 years' experience in a research or clinical laboratory.
• Proficiency in molecular biology and clinical genetics.
• Experience with ACMG variant classification guidelines is advantageous.

Responsibilities

• Analyze and interpret genetic variations from lab reports.
• Prepare information for multidisciplinary team meetings.
• Maintain the in-house database of genetic variants.
• Work with bioinformatics to improve workflows.
• Contribute to writing scientific publications.

Skills

Clinical genetics

Variant interpretation

Molecular biology

Variant classification guidelines

Education

Master of Science in a life sciences-related field

Job description

A Variant Scientist position is available at KK Women’s and Children’s Hospital (KKH) for experienced candidates with experience in clinical genetics and clinical variant interpretation. The successful candidate will be part of the team responsible for analysis and interpretation of genetic variation identified by internal and external laboratories, with the aim of delivering accurate and comprehensive clinical genetic testing reports to patients and their care providers.

Other responsibilities include:

• Prepare relevant information for multidisciplinary team (MDT) meetings to enable proper classification of variants.
• Ensure the in-house database of genetic variants is kept up to date, and that periodic variant re-analysis is performed.
• Work closely with the bioinformatics team to develop and improve bioinformatics workflows.
• Provide domain knowledge expertise and training on variant curation best practices to colleagues of all levels.
• Participate in the writing of scientific publications to ensure that novel findings are disseminated.

Requirements

• Master of Science in a life sciences-related field or relevant qualification.
• Minimum of 3 years' experience (either in a research or clinical laboratory) with relevant work experience, including molecular genetics.
• Previous experience and proficiency in the application of variant classification guidelines (e.g., ACMG) would be advantageous.
• Proficiency in molecular biology, clinical genetics is relevant.

We regret to inform that only shortlisted candidate will be notified via email.