Scientist (LS Lab), IMCB

Agency for Science, Technology and Research (A*STAR); Singapore; On-site; USD 60,000 - 100,000; Full time

Job summary

An established research institute is seeking a passionate PhD graduate to join a dynamic team focused on revolutionary drug discovery. In this full-time, on-site role, you'll collaborate closely with leading scientists to explore innovative approaches in molecular glues, enhancing therapeutic development. This position offers a unique opportunity to contribute to groundbreaking research while receiving strong support for your professional growth and career development. If you're self-motivated and eager to make a significant impact in the scientific community, this role is perfect for you.

Qualifications

• PhD in a relevant field is essential for this role.
• Strong skills in molecular biology and protein chemistry are crucial.

Responsibilities

• Conduct pioneering drug discovery initiatives focusing on molecular glues.
• Work closely with Dr. Liu on experimental design and execution.

Skills

Molecular Biology

Protein Chemistry

Biophysical Assays

Cellular Assays

Computational Skills

Education

PhD in Chemistry

PhD in Chemical Biology

PhD in Biochemistry

PhD in Biophysics

PhD in Biology

Tools

DNA-encoded Library Screening

Protein Expression Systems

Job description

The Institute of Molecular and Cell Biology (IMCB) is a premier research institute at A*STAR in Singapore. This is a full-time on-site role in Shuang Liu"s lab at IMCB. You will work closely with Dr Liu on pioneering drug discovery initiatives, focusing primarily on molecular glues — small molecules capable of inducing non-native protein-protein interactions to advance next-generation therapeutics. Our goal is to revolutionise small-molecule drug discovery, with strong support for your professional growth and long-term career development.
Key techniques:

• State-of-the-art DNA-encoded library screening
• Recombinant protein expression and purification
• Biophysical and cellular assays for molecular glues

Requirements:

• PhD in Chemistry, Chemical Biology, Biochemistry, Biophysics, Biology, or a relatedfield
• Computational skills are a plus
• Self-motivated with a strong intellectual curiosity in scientific research
• Proficiency in conducting meticulous experiments
• Good organisational and presentation skills