Working week: 5.5 days
Working Hours: Monday to Friday – 9 am to 6 pm and Saturday - 9 am to 1 pm
Salary Ranges: Monthly Salary: S$16,500 to S$18,000
Summary:
The CEO will establish and run Singapore’s first integrated longevity-focused translational hub for the Company, overseeing every stage from hypothesis-driven discovery through IND-ready manufacturing for age-modifying therapeutics and diagnostics. Success demands a rare blend of deep geroscience know-how, cross-jurisdictional regulatory mastery, and venture-financing experience that aligns with the parent group’s global IP and capital-market strategy.
Key Responsibilities:
A. Scientific & Clinical Strategy
- Draft and execute a 5-year programme that converts hallmarks-of-ageing research into first-in-human candidates.
- Integrate multi-omics, AI-driven target discovery, and large-animal longevity models within GLP workflows.
- Synchronise Singapore R&D with parallel GMP efforts in the UK and US.
B. Capital Formation & Governance
- Lead equity and convertible-note rounds totalling > US$5 million within 18 months.
- Structure cross-border IP-holding and grant-funding vehicles to maximise Singapore RIE incentives and Section 13R tax benefits.
- Chair the Audit & Risk Committee; oversee quarterly board packs.
C. Operations & Compliance
- Commission a BSL-2/ISO-7 cleanroom and ensure readiness for HAS and EMA inspections.
- Implement ISO-27001 aligned data-integrity systems for multi-site pre-clinical studies.
- Maintain 100% adherence to MOM fair employment guidelines and TAFEP best practices.
D. Talent & Culture
- Build a lean team (< 15 FTEs in year 1) spanning bioinformatics, CMC, clinical operations, and finance.
- Introduce a 24-month rotational leadership development plan and continuous-learning stipends tied to milestone KPIs.
- Negotiate ecosystem partnerships with ASTAR institutes, local CDMOs, and Temasek-linked venture funds. Act as company spokesperson at global geroscience consortia and Singapore Week of Innovation & Technology (SWITCH).
Job Requirements:
A. Experience
- > 8 years senior leadership (VP, GM, or C-suite) in venture-backed therapeutics or diagnostic start-ups.
- Demonstrable full-cycle advancement of at least one aging-modulation asset to IND or CE-IVD/510(k) filing.
- Hands-on responsibilities for raising > US$5 million in external capital.
- Direct oversight of multi-jurisdictional regulatory filings (HSA plus at least one of GDA/EMA/MHRA).
B. Technical Exposure
- Working familiarity with geroprotective modalities (e.g., NAD+ boosters, senolytics, epigenetic reprogramming, telomere maintenance) and associated CMC challenges (viral-vector or LNP delivery, sterile-fill finish, stability).
- Competence in drafting data-room materials for longevity VC due diligence and sovereign-wealth co-investment.
C. Leadership & Soft Skills
- Strategic thinker capable of translating complex biology into investable milestones under tight capital constraints.
- Adept at navigating matrixed, cross-time zone governance structures and high-velocity change environments.
- Uncompromising professional ethics and risk-management discipline.
D. Mobility
- Willing to undertake frequent travel (up to 40%) to the UK, EU, and US for board meetings, clinical-site qualification, and partner negotiations.
- After-hours availability for global time-zone calls, coordination with Europe/US, and readiness for urgent board interventions.