Biotechnologist (Purification)

Tek Systems; Singapore; On-site; SGD 45,000 - 70,000; Full time

Job summary

A leading company in the biotechnology sector is seeking a motivated Biotechnologist to manage purification operations and ensure compliance with GMP guidelines. The role involves operating advanced chromatography systems and maintaining meticulous process documentation, contributing to the production of high-quality biologics. Ideal candidates will have a background in Biotechnology or related fields, with a strong emphasis on aseptic techniques and hands-on experience in purification processes.

Qualifications

• Studied in Biotechnology, Biochemical Engineering, or related field.
• Hands-on experience in chromatography preferred.
• Familiarity with GMP, GCP, and GDP standards required.

Responsibilities

• Operate purification systems and execute chromatography steps.
• Follow SOPs and maintain compliance with documentation standards.
• Assist in troubleshooting and process improvements.

Skills

Chromatography

Purification Operations

Aseptic Techniques

Documentation Compliance

Process Troubleshooting

Education

Degree in Biotechnology

Biochemical Engineering

Microbiology

Tools

AKTA Systems

Job description

• Chromatography & Purification Operations (Core Focus)
• Process Documentation & Compliance
• Operate purification systems such as AKTA, TFF units, and chromatography columns (affinity, ion exchange, SEC, HIC).

Role Summary

We are looking for a motivated Biotechnologist, you will execute routine and critical manufacturing operations within the Purification area, ensuring consistent production of clinical and/or commercial biologics. You will operate and maintain bioreactors and related equipment in compliance with GMP guidelines and SOPs, contributing to process reliability and product quality.

Key Responsibilities

• Chromatography & Purification Operations (Core Focus)
  • Operate purification systems such as AKTA, TFF units, and chromatography columns (affinity, ion exchange, SEC, HIC).
  • Prepare and formulate buffers, execute chromatography steps, and conduct in-process sampling and analytics (e.g., pH, conductivity).
  • Carry out column packing/unpacking, membrane filtration (UF/DF), and cleaning-in-place (CIP) routines.
  • Record activities and process parameters in electronic batch records (EBRs) or paper-based documentation according to cGMP standards.
  • Assist in troubleshooting purification deviations and contribute to root cause analysis.
• Process Documentation & Compliance
  • Follow detailed SOPs, Master Batch Records (MBRs), and work instructions to ensure accurate and compliant operations.
  • Participate in process improvements, documentation updates, and equipment validation support where necessary.
  • Maintain proper housekeeping, 5S standards, and cleanroom protocols in purification suites..

Must-Have Qualifications

• Studied in Biotechnology, Biochemical Engineering, Microbiology, or related life-science field.
• Minimally internship experience of hands-on experience in chromatography.
• Familiarity with GMP, GCP, and GDP standards in a biologics manufacturing environment.
• Strong aseptic technique and cleanroom behavior.
• Candidates with hands-on exposure to AKTA systems, column chromatography, or membrane-based separation will be strongly preferred.
• Proficient in documentation.

We regret to inform that only shortlisted candidates will be notified.

EA Registration No: R22109832, LEE YAO HONG MALCOLM

Allegis Group Singapore Pte Ltd, Company Reg No. 200909448N, EA License No. 10C4544