Associate Manufacturing Engineer - Cell Culture

WuXi XDC; Singapore; On-site; SGD 40,000 - 70,000; Full time

Job summary

A leading biotechnology firm in Singapore is seeking a qualified individual to engage in industrial-scale antibody manufacturing. Responsibilities include cultivating antibody intermediates, ensuring GMP compliance, and participating in shift production. The ideal candidate will have a diploma in a relevant field and strong communication skills, with opportunities for significant career development in a supportive environment.

Benefits

Comprehensive in-house training

Opportunity for internal job rotation

Mentorship program

Qualifications

• Diploma or higher qualification in a relevant field.
• Ability to adapt to a GMP cleanroom environment.
• Willingness to accept temporary assignments and overtime.

Responsibilities

• Cultivate and express antibody intermediates at industrial scale.
• Perform cell expansion and manufacturing in accordance with GMP.
• Monitor processes and ensure compliance with quality regulations.

Skills

Scientific reasoning

Methodical work habits

Strong execution and planning abilities

Good communication ability

Education

Diploma or higher in Biological, Chemical, Pharmaceutical Engineering

Job description

Responsibilities

• Cultivate and express antibody intermediates in an industrial-scale cell culture platform using single-use technologies.
• Perform vial thawing, cell expansion and passage, cell culture, and harvest manufacturing in drug substance facilities in accordance with GMP requirements.
• Operate equipment and appliances following the guidance of SOPs and relevant documents.
• Prepare relevant documents, such as production batch records, SOPs, and validation reports.
• Communicate and resolve any inconsistencies and/or anomalies in production operations.
• Monitor processes, including real-time review of process parameters and process data/trends.
• Ensure that the manufacturing operations for drug substances comply with quality and safety regulations.
• Perform other tasks assigned by leadership.
• Participate in shift production as required and ensure that shift production meets SOP requirements.

Requirements

• Diploma or higher qualification in Biological, Chemical, Pharmaceutical Engineering, or other related specialties; candidates with equivalent work experience will also be considered.
• Possess thorough scientific reasoning and methodical work habits, with strong execution and planning abilities.
• Ability to adapt to a GMP cleanroom environment, including the requirement to wear dust-free clothing, masks, and goggles.
• Possess good communication ability and comprehension ability.
• Display a good working attitude, strong work ethic, and willingness to follow leadership directives.
• Be open to accepting temporary work assignments, including overtime on weekends or weekdays, and other roles as required.

Career Development

• Comprehensive in-house training program (E-learning / OJT / Mentorship)
• Dual career development tracks – Professional & Managerial Tracks
• Opportunity for internal job rotation / Cross-BU transfer / Cross-country assignment
• Cross cultural learning
• GMP greenfield start-up experience