AnT1 Trainee - Biotechnologist, MFG (CGT)

Lonza Biologics Tuas Pte Ltd; Singapore; On-site; Confidential; Full time

Job summary

Lonza Biologics Tuas Pte Ltd in Singapore seeks a Biotechnologist as part of the CCP training program. The role supports CGMP cell therapy production, working within a clean room alongside a large technical team to execute production activities from media prep to final filling and cryopreservation.

Thorough on‑the‑job training is provided, with rotation through day, weekend and public holiday shifts. Ideal candidates have a science/engineering degree and an interest in cell culture, aseptic

Qualifications

• Degree/ Diploma in a related Science/ Engineering discipline.
• Knowledge of cGMP applications.
• Knowledge of cell culture and aseptic processing within a classified environment.
• Willing to perform rotating 12-hour shift pattern.

Responsibilities

• Complies with site/department EHS standards and regulations.
• Attains understanding of CGMP and clean room practices.
• Maintains in-operation production facilities, equipment, and monitoring tasks.
• Prepares media, performs aseptic filtration, and handles cell culture steps.
• Performs formulation, filling of vials, inspection, and cryopreservation.
• Participates in aseptic process simulations and records documentation.
• Engages in environmental monitoring and media bag handling.

Skills

Strong communication

Team oriented

Interpersonal skills

Adaptability

Willing to rotate shifts

Education

Science/Engineering degree or diploma

Job description

The Career Conversion Program (CCP) training period lasts for 15 months. Structured on-the-job training (OJT) will be provided and conducted at the participating companies to facilitate the application of learning and to ensure that individuals acquire necessary competencies to perform at their job.

The Biotechnologist role is responsible for the manufacture of therapeutic cell products under CGMP conditions. Working closely with a team of up to 40 technical, SME and supervisor/manager colleagues, Cell Therapy Biotechnologists are expected to execute CGMP Cell Therapy production activities through to filling of final dose product within a stringent CGMP clean room environment. As a member of the Cell Therapy Manufacturing team the aim of this position is to develop expert technical knowledge and flawless execution of the Cell Therapy production process.

Production activities occur in the classified production suite which requires change into cleanroom clothing and compliance with clean room standards. This includes removal of jewelry/make-up, donning of over suits/coveralls, safety shoes, shoe covers/booties, hair cover, gloves and safety glasses/shield.

What you'll do:

This position could be an ideal opportunity for someone with an interest in Cell Therapy production wanting to develop their production career in a different technical/scientific area. Thorough training and continual assessment will be provided. After training successful applicants would be expected to join day, weekend and public holiday rotation shift. (12 hours)

• Complies with site/department EHS standards (policies, rules and regulations).
• Attains a thorough understanding of the principles of CGMP compliance and clean room practices.
• Contributes to appropriate maintenance of 'in-operation' production facilities and equipment. g. cleaning & sanitization, equipment monitoring, sampling, pH and conductivity checks.
• Solution and medium preparation followed by aseptic filtration into sterile containers.
• Revival and culturing of anchorage dependent cell lines in static flasks and cell factories.
• Harvest and concentration of cell factory generated cell cultures using tangential flow filtration or/and centrifugation.
• Final formulation and filling of vials. Visual inspection and cryopreservation.
• Participation in aseptic process simulations.
• Accurate and thorough completion of batch record documentation.
• Environmental monitoring (viable particulates, nori-viable particulates, surface and operator).
• Formulation of media and aseptic filling of media bags and bottles

Education & Experience

• Degree/ Diploma in a related Science/ Engineering discipline
• Individual without prior working experience in the biopharmaceutical manufacturing industry is encouraged to apply as training will be provided
• Knowledge of cGMP applications
• Knowledge of cell culture and the principles of aseptic processing within a classified environment.
• Strong team oriented work ethic
• Positive team oriented attitude
• Strong communication and interpersonal skills
• Willing to perform rotating 12-hour shift pattern
• Able to perform physical activities in a clean room environment. Individual will be on the feet most of the time, and will be required to perform manual work (> 60% of activities) in a buddy system that includes standing, carrying items that weigh up to 12 kg, or moving equipment.

About Lonza

At Lonza, our people are our greatest strength. With 30+ sites across five continents, our globally connected teams work together every day to manufacture the medicines of tomorrow. Our core values of Collaboration, Accountability, Excellence, Passion and Integrity reflect who we are and how we work together. Everyone’s ideas, big or small, have the potential to improve millions of lives, and that’s the kind of work we want you to be part of.

Innovation thrives when people from all backgrounds bring their unique perspectives to the table. At Lonza, we value diversity and are committed to creating an inclusive environment for all employees. If you’re ready to help turn our customers’ breakthrough ideas into viable therapies, we look forward to welcoming you on board.