Postdoctoral studies in in single-cell and computational biology (scholarship)

Karolinska Institutet; Solna kommun; On-site; SEK 502,000 - 614,000; Full time

Job summary

Karolinska Institutet seeks a highly motivated Computational Biologist at the postdoctoral level to investigate molecular landscapes of pain-related conditions. The role combines experimental and computational approaches, with a focus on single-cell RNA and ATAC sequencing and spatial transcriptomics.

The candidate will collaborate across a multidisciplinary program, manage data, develop analytical tools, and contribute to manuscripts and grant applications.

Qualifications

• Strong background in bioinformatics, statistics, and computational biology.
• Proven experience with statistical and bioinformatics software.
• Fluency in English, written and spoken.

Responsibilities

• Perform bioinformatics analyses with emphasis on single-cell RNA and ATAC sequencing and spatial data.
• Develop code and novel tools for advanced data analysis and visualization.
• Manage data quality control, storage, and archival processes.
• Collaborate with PhD students and postdocs and communicate results to diverse audiences.
• Contribute to manuscript and grant writing and prepare scientific presentations.

Skills

Bioinformatics

Single-cell RNA-seq

Single-cell ATAC-seq

Spatial Transcriptomics

Python

R

Education

Ph.D. in computational biology

Job description

Postdoctoral studies in in single-cell and computational biology (scholarship)

Postdoctoral studies single-cell and computational biology(scholarship)

Do you want to contribute to better health for all?

A postdoctoral position is available in the laboratory of Saida Hadjab at the Department of Neuroscience, Karolinska Institutet, to investigate the molecular landscape of chronic pain and headache disorders under various physiological and pathological conditions. The successful candidate will join a multidisciplinary research program that combines experimental models, patient-derived materials, and advanced technologies to explore the mechanisms that lead to persistent pain disorders.

Division

The role is situated within the Neurobiology of Pain & Therapeutics research group, led by Saida Hadjab. Our group focuses on uncovering the molecular and cellular mechanisms that maintain sensory system homeostasis, and how disruptions in these processes contribute to sensory dysfunction. The lab employs a broad range of techniques – including viral tracing, advanced single-cell approaches, and in vivo behavioral analyses – to dissect the organization and function of sensory circuits.

Duties

We are seeking a highly motivated Computational Biologist at the postdoctoral level to join our team. The primary responsibilities include bioinformatics analyses (including integration of multiple dataset) with a strong focus on single-cell RNA and ATAC sequencing and spatial transcriptomic data. A demonstrated interest in data visualization and large-scale data analysis is highly desirable.

The ideal candidate will have a keen interest in understanding complex biological systems, their development, and how disruptions in homeostasis contribute to pathological conditions. The position involves close collaboration with PhD students, postdoctoral researchers, and international partners, therefore the candidate is expected to be multitasking as projects will progress in parallel. Active participation in other ongoing projects in the lab and clear communication of research findings to both specialized and general audiences are expected.

Additional responsibilities include: performing data quality control, management, and archival storage; analyzing large-scale datasets, developing code, and creating novel tools and methods for advanced data analysis; supporting ongoing research activities, contributing to manuscript and grant writing, and preparing presentations for scientific meetings; helping shape, maintain, and develop the group’s computational infrastructure.

Entry requirements

Postdoctoral scholarships may be established for foreign researchers who pursue their merit in Sweden. A foreign researcher is a person living in another country who comes to Sweden with the intention of only staying in Sweden for all or part of their postdoctoral education at KI. Persons who are resident in Sweden and/or have carried out all or part of their academic education at KI or some other educational institution in Sweden cannot be considered for scholarships. The purpose of scholarships for postdoctoral qualification is to promote internationalization and contribute to research qualification after a doctorate or equivalent. A scholarship for carrying out postdoctoral research can be granted for a maximum of two years within a four-year period following the receipt of a doctoral degree or equivalent. To be eligible for a postdoctoral scholarship, the person must have obtained a doctorate, or a foreign degree deemed to be equivalent to a doctorate. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) start date of the post-doctoral education.

The ideal candidate will have a strong background in bioinformatics, statistics, and computational biology, with demonstrated expertise in statistical and bioinformatics software. The ability to thrive in a multidisciplinary research environment and to communicate effectively with team members is essential. Candidates should be highly motivated, capable of working independently, and collaborative in nature.

A strong publication record in reputable peer-reviewed journals is highly desirable. Proficiency in programming, particularly in R, Python, or other relevant languages, is required.

Qualified candidates should also meet the following criteria: a Ph.D. or M.D./Ph.D. in computational biology, or in biomedical sciences with a strong computational focus; proven ability to think creatively and solve complex problems with persistence and initiative; excellent communication skills, both written and oral; solid molecular and cell biology knowledge and a strong foundation in biomedical research; fluency in English, both spoken and written.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. Here, we conduct innovative medical research and provide the largest range of biomedical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Students and employees have free access to our modern gym facilities with trained staff on site.

The amount is tax free and it is set for twelve months at a time, paid out on a six months basis. In exceptional cases, shorter periods may be acceptable.