Postdoc: Microfluidics & SANS for Therapeutic Nanoparticles

Karlstad University; Göteborgs kommun; On-site; SEK 420,000 - 540,000; Full time

Benefits offered by this job

Employee benefits

Swedish courses

Coastal city of Gothenburg

Job summary

Chalmers University of Technology in Gothenburg invites applications for a postdoctoral position to design a microfluidics setup for studying lipid and polymer-based nanoparticles under flow, using small angle neutron scattering at ESS. The project is a collaboration with the Holme group, Stubelius group, and international partners.

You will work independently and with colleagues to develop structure–function relationships in therapeutic delivery systems, supervise master’s/PhD students to some

Qualifications

• A doctoral degree in a relevant field such as soft matter, biophysics, materials science, nanomedicine, chemistry, or related disciplines, or an equivalent foreign degree. Must be obtained no later than the time the employment decision is made.
• Strong written and verbal communication skills in English.
• Experience in microfluidics for nanoparticle characterisation.
• Strong analytical skills, experience with interdisciplinary research, and ability to work independently and collaboratively.
• Experience (meritorious) if the doctoral degree has been obtained within the last three years prior to the application deadline.
• Experience in using neutrons or X-rays to study soft or hard matter at large‑scale research infrastructures.
• Experience in in‑vitro experiments to characterise nanoparticle therapeutic efficacy.
• Experience in molecular dynamics simulations (coarse grain or all atom) and working knowledge in Python.

Responsibilities

• Develop a microfluidics system to be employed at small angle scattering beamlines at the ESS to study nanoparticle structures and interactions under various biologically relevant conditions.
• Understand how surface functionalisation, protein corona formation, and glycosylation influence the structure and biological function of lipid‑ and polymer‑based nanocarriers.
• Collaborate with group members with expertise in small‑angle neutron scattering (SANS), in‑vitro characterisation, and molecular dynamics simulations to establish structure–function relationships in advanced therapeutic delivery systems.
• Supervise master’s and/or PhD students to a certain extent.
• Position is based at Chalmers University of Technology, in Gothenburg, and occasional travel to the ESS in Lund for periods of up to a week at a time for beamtime experiments.

Skills

Microfluidics

Interdisciplinary research

English proficiency

Independent work

Nanoparticle characterisation

In‑vitro experiments

Molecular dynamics simulations

Python

Education

Doctoral degree in soft matter/biophysics/chemistry or related field

Experience within last 3 years (meritorious)

Tools

Python

Job description

Chalmers University of Technology in Gothenburg invites applications for a postdoctoral position to design a microfluidics setup for studying lipid and polymer-based nanoparticles under flow, using small angle neutron scattering at ESS. The project is a collaboration with the Holme group, Stubelius group, and international partners.

You will work independently and with colleagues to develop structure–function relationships in therapeutic delivery systems, supervise master’s/PhD students to some