Postdoctoral Researcher, Biological Interactions of Lipid Nanoparticles

Big Science Sweden; Danmark; Hybrid; SEK 390.600 - 558.000; Vollzeit

Zusammenfassung

Big Science Sweden söker en postdoktor för att undersöka biologiska interaktioner av lipidnanopartiklar inom projektet "Lifecycle of a Lipid Nanoparticle". Rollen inkluderar att utveckla experiment och modellssystem som används för analyser på ESS i Lund.

Den framgångsrika kandidaten förväntas ha erfarenhet av lipid biophysics och laboratoriemetoder, samt att arbeta med ett samarbetsprojekt inkluderande flera forskningsinstitutioner. Tjänsten innebär starka samarbeten och deltagande i konsortiemöten.

Qualifikationen

• Erfarenhet av lipid biophysics och relaterade laboratoriemetoder.

Aufgaben

• Utveckla proof-of-concept experiment för studier på lipidnanopartiklar.
• Bygga modellmembransystem av biologisk relevans för dessa studier.
• Delta i regelbundna konsortiemöten och rapportera resultat.

Kenntnisse

Lipid biophysics

QCM-D

Optical spectroscopies

Ellipsometry

SPR

TIRF

Jobbeschreibung

Postdoctoral Researcher, Biological Interactions of Lipid Nanoparticles

Datum: 10 juli, 2026 Tid: 11:59

Placering: ESS

Mer information

The role is part of the Vetenskapsrådet funded ESS Science Initiative project “Lifecycle of a Lipid Nanoparticle”, which is a consortium of Swedish and international researchers from universities, research institutes, and industry with a common interest in the underlying behaviours of lipid nanoparticles as drug delivery vectors.

The goals of this part of the project are:

• Develop an understanding of the biological interactions of lipid nanoparticles
• Develop model systems and measurement protocols that can be used to enable experiments on lipid nanoparticles at ESS.

To achieve these goals, the postdoctoral researcher will develop proof-of-concept experiments to be run on the Estia neutron reflectometry instrument at ESS. The work will involve the development of model membrane systems of biological relevance for these studies, building on existing work within the community. To achieve this, we will make use of commercially available lipids as well as lipid extracts available from the ESS Deuteration Facility. The successful candidate will have experience in lipid biophysics and associated laboratory characterisation methods such as QCM-D, optical spectroscopies, ellipsometry, SPR, and TIRF.

Whilst the primary location for the work will be at ESS in Lund, working with Dr. Tom Arnold and Dr. Sebastian Jaksch, this project will be co-supervised by Dr. Margaret Holme at Chalmers University of Technology in Gothenburg as well as other research consortium labs, and strong interactions with the academic partners will be expected. There will be regular consortium meetings, including reporting of your results to the team.