Postdoc in computational biophysics

KTH Royal Institute of Technology; Stockholms kommun; On-site; SEK 390,600 - 468,720; Full time

Job summary

KTH in Stockholm invites applications for a postdoctoral fellow to study Kv7 ion channels. The project focuses on developing activators and inhibitors, using molecular dynamics simulations of channels bound to modulators, within a broad collaborative effort spanning cryo-EM, electrophysiology, behavioral experiments and machine learning.

The position is temporary up to three years and is intended as a first career step after a dissertation.

Qualifications

• Doctoral degree or equivalent must be completed by time of employment decision
• Experience with molecular dynamics simulations
• Experience working in collaborative work environments
• Research expertise
• Awareness of diversity and equal opportunity issues, with focus on gender equality
• Independence
• Doctoral degree or equivalent obtained within last 3 years (preferred)
• Teaching abilities (preferred)
• Collaborative abilities (preferred)
• Experience with enhanced sampling simulations and coarse grained force fields (preferred)
• Experience with biological systems including membrane proteins (preferred)

Responsibilities

• Conduct molecular dynamics simulations of ion channels bound to various modulators
• Integrate results within a collaborative project with multiple research teams
• Contribute to interdisciplinary research including cryo-EM, electrophysiology, behavioral experiments and machine learning
• Engage in data analysis and interpretation across techniques

Skills

Molecular dynamics

Collaborative work

Independence

Research expertise

Diversity & equality awareness

Education

Doctoral degree or equivalent

Job description

Job description

Ion channels are essential for life across organisms and a sophisticated understanding of their function is imperative for basic, biomedical and applied research. The overarching goal of the proposed project is to develop ion channel activators and inhibitors. Previously unmet specificity needs will be achieved by targeting subtype- and conformational-specific features, thereby limiting side effects. The focus will be on Kv7 channels linked to a range of severe neurological disorders, including epilepsy, sleep disorders and autism.

The postdoc will carry out molecular dynamics simulations of these channels bound to various modulators, and integrate the results within a collaborative project with four other research teams carrying out cryo-electron microscopy, electrophysiology, behavioral experiments and machine learning.

Qualifications

Requirements

• A doctoral degree or an equivalent foreign degree. This eligibility requirement must be met no later than the time the employment decision is made.
• Experience with molecular dynamics simulations
• Experience working in collaborative work environments
• Research expertise
• Awareness of diversity and equal opportunity issues, with specific focus on gender equality
• Independence

Preferred qualifications

• A doctoral degree or an equivalent foreign degree, obtained within the last three years prior to the application deadline
• Teaching abilities
• Collaborative abilities
• Experience with enhanced sampling simulations and coarse grained force fields
• Experience with biological systems including membrane proteins

Great emphasis will be placed on personal skills.

Join us at KTH

KTH shapes the future through education, research and innovation. As a leading international technical university, we play an active role in advancing the transition towards a sustainable society. At KTH, you have the opportunity to grow and develop in a creative and dynamic environment, with good working conditions and attractive benefits. Equality, diversity and equal opportunities are essential to quality and form an integral part of KTH’s core values as a university and public authority.

Learn more about our benefits and what it's like to work and grow at KTH.

Trade union representatives

Contact information to trade union representatives.

To apply for the position

Log into KTH's recruitment system to apply for this position. You are responsible for ensuring that your application is complete according to the instructions in the ad.

The application must include:

• CV including relevant professional experience and knowledge.
• Brief account of why you want to conduct research, your academic interests and how they relate to your previous studies and future goals. Max two pages long.

Your complete application must be received at KTH no later than the last day of application, midnight CET/CEST (Central European Time/Central European Summer Time).

About the employment

The position offered is for, at the most, three years.

A position as a postdoctoral fellow is a time-limited qualified appointment focusing mainly on research, intended as a first career step after a dissertation.

Other information

For information about processing of personal data in the recruitment process.

It may be the case that a position at KTH is classified as a security-sensitive role in accordance with the Protective Security Act (2018:585). If this applies to the specific position, a security clearance will be conducted for the applicant in accordance with the same law with the applicant's consent. In such cases, a prerequisite for employment is that the applicant is approved following the security clearance.

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Disclaimer: In case of discrepancy between the Swedish original and the English translation of the job announcement, the Swedish version takes precedence.

Type of employment: Temporary position
Contract type: Full time
First day of employment: According to agreement
Salary: Monthly salary
Number of positions: 1
Full-time equivalent: 100%
City: Stockholm
County: Stockholms län
Country: Sweden
Reference number: PA-2026-1887
Contact:

1. Lucie Delemotte, [e-mail]

Published: 2026-05-26
Last application date: 2026-06-16

Fields: Molecular Biology, Computational Biology, Biophysics, Computational Physics, Neurology