Senior Specialist – Research Engineer in the Quantitative Virology Research Group

Łukasiewicz – PORT Polski Ośrodek Rozwoju Technologii; Wrocław; Hybrid; PLN 150,000 - 190,000; Full time

Benefits offered by this job

Free parking

Private medical care

Sports card

Group life insurance

Social Benefits Fund

Green science campus

Paid leave for research division

Job summary

Łukasiewicz – PORT Polski Ośrodek Rozwoju Technologii poszukuje kandydatów na stanowisko postdoktoralnego w zespole Quantitative Virology Research Group. Praca obejmuje tworzenie modeli deep learning do przewidywania środowisk molekularnych rezerw HIV i analizę zestawów danych metagenomicznych.

Badania obejmują integrowanie danych epidemiologicznych i populacyjnych oraz rozwijanie pipeline’u PORT-EK. Praca zespołowa, możliwość przedłużenia umowy i rozwój zawodowy w przyjaznym środowisku

Qualifications

• Doktorat w dziedzinie odpowiadającej profilu badawczego.
• Znajomość Pythona, dodatkowe języki programowania (np. R) będą pożądane.
• Doświadczenie w projektach z zakresu modeli opartych na deep learning i modelowania in silico z danymi metagenomicznymi lub populacyjnymi.

Responsibilities

• Prowadzenie prac badawczych nad modelami opartymi na głębokim uczeniu i ich zastosowanie w genomice.
• Analiza i modelowanie danych ‘omics’ w kontekście epidemiologii i populacyjnej genetyki.
• Współpraca w zespole, udział w szkoleniach nowo przyjętych pracowników.

Skills

Python

R

Deep learning

Bioinformatics

Education

Ph.D. in computational science, mathematics, physics

Tools

PORT-EK

Job description

TRYB PRACY: STACJONARNA

-Ph.D. in computational science, mathematics, physics or relevant fields.

-At least one first-author peer-reviewed research article.

-Working knowledge of Python; knowing additional programming languages (e.g., R) will be appreciated.

-Anticipating projects related to constructing deep learning-based models and in silico modeling with metagenomics datasets or with population genetics datasets.

-Task-oriented person and a team worker.

-Good communication skills in English (written and spoken).

The candidate must meet the requirements of the NCN project Regulations, in particular by obtaining their doctoral degree in the year of employment in the project or within 7 years prior to 1 January of the year of employment in the project.

This period may be extended by the time spent during that interval on long-term (over 90 days) documented sick leave or on rehabilitation benefits due to incapacity for work. Additionally, it may be extended by the number of months spent on childcare-related leave granted under the Labour Code. In the case of women, this period may also be extended by 18 months for each child born or adopted, if this method of accounting for breaks in the academic career is more favourable.

The successful applicant will work in an established laboratory and join a collaborative, vibrant, and growing community of researchers in an environment that values creativity and scientific communications in Łukasiewicz–PORT. In our team, we carry on both wet-lab experiments and dry lab bioinformatics analyses. The candidate will join scientific discussions with other team members. Together with the team leader, the candidate will help with training newcomers. Overall, the candidate will have a great opportunity to participate in research on training and gain knowledge and skills for his/her career development. This position offers the potential for contract extension.

The Quantitative Virology Research Group in Łukasiewicz–PORT invites applications for a postdoctoral position starting as soon as possible. We are recruiting applicants with broad research interests to work on Big Data, multigenomic studies, and computational modeling.

The candidate will join ongoing projects in our team and perform mathematical/computational modeling. The topics include (1) constructing deep learning-based models to predict the molecular microenvironments of the latent HIV reservoir and (2) profiling the landscapes of enriched antisense RNA k-mers across HIV-1 subtypes.

Our laboratory has proposed the presence of distinct molecular microenvironments in the latent HiV reservoir (Chen H. 2026. J Virol 100:e00175-26), which leads to the heterogeneous nature of the reservoir configuration. The candidate will apply an array of “omics” datasets generated in the lab to construct deep learning-based models, enabling the classification and prediction of distinct microenvironments and seek critical predictor attributes in defining distinct microenvironments.

In addition, our lab previously established the streamlined pipeline named the Pathogen Origin Recognition Tool using Enriched K-mers (PORT-EK) ( https://github.com/Quantitative-Virology-Research-Group/PORT-EK-version-2 ), which is a k-mer-based approach, facilitating the comparison of various multigenomic datasets and detecting over-represented genomic regions (i.e., k-mers) linked to specific sequences (Wiśniewski and Chen 2025 IMetaOmics PMID: 41675161; Wiśniewski et al. 2026 BioRxiv DOI:10.64898/2026.02.25.707904). The candidate will further reinforce the pipeline to identify enriched k-mers using HIV-1 antisense transcripts across subtypes. In parallel, the candidate will work on exploring epidemiological models within the framework of phylodynamics and phylogeography and integrating them with population genetics models. Increasing the performance of integration algorithms and model simulations, and developing machine learning methods for analyzing genomic data.

Computational/mathematical modeling and bioinformatic analysis

• Full-time employment on the position ofSenior Specialist.
• Work in a scientificresearch organization focused on the implementation of innovativeR&D projects.
• Co-financing for private medical care.
• Co-financing for a sports card.
• Possibility to join group life insurance.
• Co-financing under the Social Benefits Fund (for holidays and Christmas).
• Work on the territory of a green science campus.
• Free parking space.
• Additional 10 days of paid leave per year for employees of the research division.