Data QC Analyst

Nexa Trials; Karachi Division; On-site; PKR 600,000 - 800,000; Full time

Benefits offered by this job

Competitive compensation

Hybrid work model

GCP refresher training

Job summary

Nexa Trials is seeking a Data QC Analyst in Karachi to oversee source-to-EDC quality operations for multi-site programs. This hybrid role involves executing quality checks, managing queries, and maintaining accurate documentation to ensure sponsor trust.

You will work closely with clinical coordinators and data managers across regions, focusing on reducing inspection risks and meeting database lock timelines. The right candidate will have a background in clinical data management and strong attention to detail.

Qualifications

• 2–4 years of experience in clinical data management or related roles.
• Working knowledge of ICH-GCP and data integrity requirements.
• Proficiency with at least one major EDC platform.

Responsibilities

• Perform source-to-EDC QC checks and identify discrepancies.
• Manage and track data queries for resolution.
• Maintain QC workbooks and monitor study portfolios.

Skills

Clinical data management

Data quality control

Communication skills

Attention to detail

Tools

NexaSource

Medidata Rave

Oracle Clinical One

Job description

Deliver centralized source-to-EDC quality operations for multi-site sponsor programs — catching discrepancies early, managing queries with precision, and maintaining audit-ready documentation across global study portfolios.

About the role

Nexa Trials operates a centralized data quality function from Karachi, supporting sponsor and CRO programs across North America, Europe, the Middle East, and South Asia. As a Data QC Analyst, you will execute source-to-EDC reconciliation, discrepancy detection, and query management for studies running on NexaSource™ capture and Nexa Bus™ automated transfers.

Quality is not a checkbox at Nexa Trials — it is how we earn sponsor trust. You will compare eSource records against EDC submissions, identify root causes of mapping errors or site documentation gaps, and drive queries to resolution with coordinators and data managers. Your work directly reduces inspection risk and keeps database lock timelines on track.

You will report to the South Asia QC Lead and collaborate with clinical coordinators in Canada, data architects in Austin, QC colleagues in Dubai, and engineering teams in Lahore. This hybrid role is based in Karachi with flexibility for remote days and occasional cross-regional sponsor meetings.

Responsibilities

• Perform systematic source-to-EDC QC checks — comparing NexaSource records, uploaded documents, and EDC field values against mapping specifications
• Identify, classify, and document discrepancies with clear evidence trails suitable for sponsor audit and inspection
• Author, route, and track data queries through resolution — coordinating with site coordinators, CRAs, and sponsor data managers
• Monitor Nexa Bus transfer logs and error reports; elevate systemic mapping or integration issues to data architecture and engineering
• Maintain QC workbooks, trend reports, and KPI dashboards for assigned study portfolios
• Support database lock readiness — final QC sweeps, query closure verification, and documentation package assembly
• Apply ICH‑GCP and ALCOA+ principles to all QC activities; flag potential protocol deviations or data integrity concerns
• Contribute to QC SOPs, checklists, and training materials that standardize quality operations across regions
• Participate in sponsor and CRO data review meetings as the Nexa Trials QC representative

Requirements

• 2–4 years of experience in clinical data management, data QC, or clinical research associate roles with substantive data review responsibility
• Working knowledge of ICH‑GCP and data integrity requirements for clinical trial data
• Experience with source-to-EDC reconciliation, manual review, or centralized monitoring workflows
• Proficiency with at least one major EDC platform and comfort navigating eSource or hybrid capture environments
• Strong attention to detail and ability to maintain accuracy across high-volume, multi-site study portfolios
• Clear written communication for query text, discrepancy narratives, and sponsor-facing QC summaries
• Eligible to work in Pakistan
• Professional working proficiency in English; Urdu language skills valued for regional site engagement

Nice to have

• Experience with NexaSource, custom eSource platforms, or automated eSource-to-EDC transfer pipelines
• Exposure to Pakistan regulatory context — DRAP requirements or regional ethics committee processes
• Familiarity with Medidata Rave, Veeva, or Oracle Clinical One query modules
• Basic SQL or Excel advanced skills for trend analysis and QC sampling
• Prior work with CRO centralized monitoring or sponsor-led data quality programs
• CDISC awareness or experience supporting SDTM-ready dataset reviews

What we offer

Be part of a growing South Asia operations hub with direct impact on sponsor programs across one of Nexa Trials' fastest-scaling delivery regions.

• Competitive compensation and Pakistan employment benefits
• Hybrid work model based in Karachi
• Exposure to NexaSource, Nexa Bus, and NexaScheduler on live multi-site studies
• Cross-regional collaboration with clinical, data, and engineering teams
• GCP refresher training and professional development support
• Career progression toward senior QC analyst, QC lead, or regional operations roles

Location

Karachi, Pakistan Region: South Asia Country: Pakistan City: Karachi Hybrid — office days in Karachi with remote flexibility