Scientist, Laboratory of Chemical Biology and Functional Genomics (GIS)

Agency for Science, Technology and Research; Queenstown; On-site; NZD 80,000 - 100,000; Full time

Job summary

A research organization in Queenstown is seeking a highly motivated Scientist to join their laboratory focused on RNA-targeted therapeutic discovery. The ideal candidate will have a PhD in Biological Sciences or related fields, with expertise in ASO design and molecular biology. Responsibilities include leading experimental design, conducting research, and maintaining lab operations. The position offers a competitive package and relocation assistance.

Benefits

Highly competitive remuneration package

Relocation assistance

Qualifications

• Receiving PhD degree within 5 years in a relevant field.
• Experience with CRISPR, ASO design, and molecular biology techniques.
• Strong organizational skills and a proactive attitude.

Responsibilities

• Lead RNA-targeting strategy design and optimization.
• Conduct experiments related to CRISPR and ASO development.
• Maintain lab operations and ensure project milestones are met.

Skills

ASO design

Molecular biology

Cell culture

RNA biology

CRISPR

Sequencing technologies

Education

PhD in Biological Sciences or Chemical Biology

Job description

Scientist, Laboratory of Chemical Biology and Functional Genomics (GIS)

Agency for Science, Technology and Research – Queenstown

The Yu Lab has an opening position for Scientist and are looking for a highly motivated Scientist to join our team and contribute to innovative RNA-targeted therapeutic discovery.

We are a chemical biology lab dedicated to translational research targeting cellular nucleic acids. This project is to engineer antisense oligonucleotides (ASOs) for gene-selective regulation, paving the way for precision medicine. By leveraging cutting-edge gene-targeting strategies, structural biology, sequencing technologies, and computational approaches, we aim to unlock RNA as precise therapeutic target, addressing diseases linked to genomic dysregulation and undruggable pathways.

Contract length: 13-month contract for the first instance

Responsibilities:

• Lead the design and optimize RNA-targeting strategies in cells.
• Lead in designing and conducting experiments related to CRISPR, small-molecule screening, and ASO development.
• Perform molecular biology experiments, including CRISPR-based gene regulation, plasmid construction, stable cell line establishment, and RNA-seq library preparation.
• Maintain lab operations, including reagent preparation, consumable ordering, budget tracking, and equipment maintenance.
• Engage in literature reviews, research discussions, and collaborative projects.
• Ensure project milestones are met and contribute to manuscript preparation.

Requirements:

• Receiving PhD degree within 5 years in Biological Sciences, Chemical Biology, or related fields.
• Experience in ASO design, molecular biology, cell culture, RNA biology, CRISPR, or sequencing technologies.
• Strong organizational skills and a positive, eager-to-learn attitude.
• Ability to work both independently and collaboratively in a fast-paced research environment.

We offer a highly competitive remuneration package and relocation assistance. Singapore is a vibrant, cosmopolitan city-state at the heart of Asia, known for its excellent quality of life, world-class research infrastructure, and strong government support for scientific innovation.

Equal Employment Opportunity: We are an equal opportunities employer and welcome applications from qualified candidates.