Research Fellow (Pharmacy and Pharmaceutical Sciences)

National University of Singapore; Queenstown; On-site; NZD 70,000 - 90,000; Full time

Job summary

A leading university is seeking a dedicated researcher to join a lab focused on biosynthetic enzymes and drug discovery. The successful candidate will conduct experiments, analyze data, and contribute to publications. This role requires a PhD and a strong interest in biochemistry, with a preference for candidates having significant research experience.

Qualifications

• Strong interest and expertise in biochemistry, enzymology, or drug discovery.
• 5 years’ experience in primary research preferred.

Responsibilities

• Design and conduct experiments in biochemistry and mRNA display.
• Prepare research findings for publication and present at conferences.
• Contribute to laboratory equipment setup and maintenance.

Skills

Biochemical Techniques

Analytical Techniques

Communication Skills

Education

PhD in Biochemistry or related field

Tools

LC/MS

HPLC

UV-Vis Spectroscopy

Job description

Job Description

The successful candidate will work in the laboratory of Dr. Alexander Vinogradov (NUS Presidential Young Professor; lab website: https://vinogradov.science) on characterizing novel biosynthetic enzymes and utilizing them for drug discovery applications. Broadly, the project is dedicated to developing an mRNA display-based platform for ultra-high-throughput analysis of post-translational modification enzymes.

The main responsibilities of the position include:

• Design and conduct experiments in biochemistry (enzymology), mRNA display, and peptide chemistry

• Analyze experimental data, including using deep learning techniques (optional)

• Prepare research findings for publication in peer-reviewed journals and presentation at international conferences

• Present oral research updates in group meetings and prepare periodic written updates

• Contribute to the setup and maintenance of laboratory equipment

Qualifications

Prospective candidates should have a strong interest and demonstratable expertise (a PhD degree supported by peer-reviewed publications) in at least one of the following areas: biochemistry, enzymology, combinatorial chemistry, deep learning, drug discovery, mRNA display, and bioorganic chemistry.

Skills:

• Expertise in basic biochemical techniques (protein expression and purification, nucleic acid work, PCR, PAGE, etc); expertise in synthetic organic chemistry is not required but will be considered an asset.

• Strong knowledge of fundamental biochemistry, enzymology, chemical kinetics is not required but will be considered an asset.

• Understanding of combinatorial chemistry concepts is not required but will be considered an asset.

• Expertise in mRNA display or other genetically encoded combinatorial methods (yeast display, phage display, DELs) is not required but will be considered an asset.

• Background in natural product research is not required but will be considered an asset.

• Familiarity with analytical and biophysical techniques (LC/MS, HPLC, UV-Vis spectroscopy, etc).

• Excellent written and verbal communication skills.

• Ability to work both independently and collaboratively within a team.

Experience:
Candidates with at least 5 years’ experience in primary research and finishing their PhD will be preferred.

More Information

Location: Kent Ridge Campus

Organization: Science

Department : Pharmacy and Pharmaceutical Sciences

Job requisition ID : 28681